Inner Banner

Principal Investigator

Dr. Jyoti Anand Kode

Principal Investigator

Honors and Recognitions

  • Received recognition as ‘Associate Professor in Life Sciences’ of Homi Bhabha National Institute, 17th August, 2021.
  • Recognition as “Outstanding Editorial Board Member” for journal World Journal of Stem Cells by Baishideng Publishing Group (BPG) Inc., USA, 17th May, 2021.
  • Invited Member, Board, Seth GS Medical College and KEM Hospital Institutional Committee for Stem Cell Research [IC-SCR]. 2020-2023.
  • Invited Member, Board of Studies for Microbiology at Sophia College (Autonomous), Mumbai, September, 2018-21.
  • Invited Editorial Board Member, World Journal of Stem Cells, Baishideng Publishing Group Inc, California, USA, April 2018- onwards
  • Received title as Assistant Professor and Faculty for mentoring research scholars for their Doctorate Degree in Life Sciences by Homi Bhabha National University, Mumbai. May 2016
  • Invited Member, Board, Reliance Life Sciences Institutional Committee for Stem Cell Research & Therapy, Dhirubai Ambani Life Sciences, Rabale, Navi Mumbai. 2011 onwards.....read more
  • Recipient of ISSCR Travel Award to present work titled “An emerging technology of Stem Cell and Chemokine therapy for cancer: Ex-vivo expansion of human CD34+ cells manipulated with a mixture of cytokines and Stromal Cell Derived Factor 1” at the 6th Annual Meeting of International Society for Stem Cell Research, Philadelphia, USA: June 10-14, 2008.
  • Received title as Post Graduate Teacher for Life Sciences Discipline by Homi Bhabha National University, Mumbai. August 2007.
  • Recipient of ISSCR Travel Award, International Travel Fellowship from Department of Biotechnology, Government of India and Immunology Foundation, New Delhi to present paper titled ”Bone Tissue Engineering using Human Mesenchymal Stem Cells: Role of SDF1-CXCR4 axis (Poster Presentation): 5th Annual Meeting of International Society for Stem Cell Research, Cairns, Australia: June 17-20, 2007
  • Recipient of fellowship from British Society of Haematology Trust, Sir Dorabji Tata Trust and Pirozshah Godrej Foundation for presenting a paper entitled, “Selective migration of IgVH3+ B-cell chronic lymphocytic leukemia clones in response to chemokine SDF1” at the 46th Annual Scientific Meeting of British Society of Haematology, Edinburgh, UK. 3-5th April 2006.
  • Recipient of Best poster presentation of the paper entitled “Distinct IgVH genotype in B-CLL cells migrating against chemokine SDF1” at the 24th Annual Convention of Indian Association for Cancer Research, and International Symposium on HPV and cervical cancer at IPCO, Noida, February 9-12, 2005.
  • Recipient of VB Kamat award for the best podium presentation of the paper entitled “Clonal T-cell receptor and gene rearrangements in T-cell acute lymphoblastic leukemia at diagnosis: Predictor of prognosis and response to chemotherapy, Indian Association for Cancer Research, January 29th-31st 2004.
  • Best Poster Presentation Award: TCR gamma-delta gene rearrangements and cytotoxic function of lymphocytes in patients with T-cell acute lymphoblastic leukemia" in the 24th Annual conference of Indian Immunology Society, Calcutta, 22-24th December 1997.
  • Dr. L.D.Sanghvi Oral Presentation Award: Interleukin-12 augments cytotoxic potential of gamma-delta T cells from patients with Chronic Myelogenous leukemia" in the 21st Annual conference of Bombay Haematology Group, Tata Memorial Centre, 15-16th March 1997.
  • Recipient of Amgen Travel grant for Young Scientists: Poster presentation on paper titled, “Interleukin-12 augments cytotoxic potential of gamma-delta T cells from patients with Chronic Myelogenous Leukaemia” at the Second Meeting of European Haematology Association, Paris, France during May 29 to June 1,1996.
  • Recipient of R.D. Birla Smarak Kosh Fellowship, Sir Dorabji Tata Trust Fellowship and Sir Ratan Tata fund for presenting a paper entitled, "Killing of mycobacteria-infected macrophages by LAK cells from leprosy patients", at the XIV International Leprosy Congress, Orlando, Florida, USA and a visit to Dr. Peter Gregersen's laboratory, Northshore University Hospital, New York, USA to learn modern molecular immunological techniques on "Analysis of TCR V CDR3 length restriction in population of CD4+ T cells". 1993.
  • Senior Research Fellowship, Council of Scientific and Industrial Research (CSIR), Government of India. 1990 to 1992.
  • Received the Best Poster award for the paper entitled, "Recognition of ICRC, M.leprae and other mycobacterial antigens by sera from leprosy patients" at the XVII Annual Conference of Indian Immunology Society, Lucknow, 1990.
  • Department of Biotechnology (previously National Biotechnology Board) Fellowship for training as a part of M.Sc. Biotechnology Course in “Hybridoma Technology” at Immunology Division, Cancer Research Institute, Mumbai: May-June 1986.
  • Junior/senior Research Fellowship, CSIR, Government of India. 1988 to 1992.
  • Department of Biotechnology (previously National Biotechnology Board) Fellowship for studying M.Sc. 1985 to 1987.
  • Open Merit Scholarship, Government of India for studying B.Sc. 1982 to 1985.

Research Interests

  • Deciphering Innate immune pathway involvement in various cancers
  • Understanding immune receptor repertoire, secretome and genomic landscape of immune cells in cancer patients on immune checkpoint blockade therapy
  • Evaluation of CD26-adenosine signaling axis in allogeneic transplant donors and recipients
  • Evaluation of soluble immune markers as prognostic biomarker for hematological and solid cancer
  • Understanding mesenchymal stem cells and leukemic blasts cross-talk in management of acute myeloid leukemia
  • Understanding mechanistic role of medicinal plant extracts in controlling leukemia growth
  • SDF1-CXCR4 signaling in hematopoietic stem cell homing and expansion
  • Exploring immunomodulatory properties and biomedical applications of natural extracts/ compounds

Event Conducted

Ongoing Research Projects

  • CD26

    CD26 and adenosine signaling pathway molecules as regulators of immune reconstitut…

    CD26 and adenosine signaling pathway molecules as regulators of immune reconstitution in… more

  • Proj3

    A study to evaluate the prognostic value of biomarkers in patients with Hodgkin…

    A study to evaluate the prognostic value of biomarkers in patients with Hodgkin’s Lympho… more

  • Proj 1

    Study of stem cell niche favoring immune evasion and maintenance of leukemia suppo…

    Study of stem cell niche favoring immune evasion and maintenance of leukemia supportive… more

  • Drug resistance in AML

    Understanding Drug Resistance in Acute Myeloid Leukemia: Role of Mesenchymal Stem…

    Understanding Drug Resistance in Acute Myeloid Leukemia: Role of Mesenchymal Stem Cells… more

  • project1

    Human tumor xenografts as in vivo testing model

    Human tumor xenografts as in vivo testing modelsmore

  • project1

    Screening of drugs for anti-cancer activity using in vivo animal models.

    Screening of drugs for anti-cancer activity using in vivo animal models.… more

  • project1

    A phase II trial to study of efficacy, toxicity and immunomodulatory effect of Car…

    A phase II trial to study of efficacy, toxicity and immunomodulatory effect of Carctol-S… more

  • AgNP

    Understanding mechanistic role of seaweed nanocomposite formulation FK-94-1 and me…

    Understanding mechanistic role of seaweed nanocomposite formulation FK-94-1 and medicinal plant extract FK-59-5… more

Lab Members

Alumni

PUBLICATIONS

Contact

Office Contact

Dr. Jyoti Anand Kode

Kode Lab, Advance Centre for Treatment Research & Education in Cancer, Tata Memorial Centre, (ACTREC), Plot No. 1 & 2, Sector 22, Kharghar, Navi Mumbai-410210. Maharashtra India.+91 (022) 2740 5000/ 6873 5000 Extn-5030 jkode@actrec.gov.in Lab Website
Back to Top