PI Publications

Quantitative proteomic analysis of different stages of rat lingual carcinogenesis

Bihari Lal Soni, Arivusudar Marimuthu, Harsh Pawar, Sharada S Sawant, Anita Borges, Ranganathan Kannan, Akhilesh Pandey, Arvind D Ingle, Hindahally Chandregowda Harsha, Milind Murlidhar Vaidya.

Clinicopathological features and prognostic implications of loss of K5 and gain of K1, K8 and K18 inoral potentially malignant lesions and squamous cell carcinomas: Immunohistochemical analysis. Online published in the Journal of Tumor Biology

Lalit Sehgal, Amitabha Mukhopadhyay, Anandi Rajan, Nileema Khapare, Mugdha Suresh Sawant, Sonali S Vishal, Khyati Bhatt, Srikant Ambatipudi, Noelle Antao, Hunain Alam, Mansa Gurjar, Srikanta Basu, Rohit Mathur, Lalit Borde, Amol S Hosing, Milind M Vaidya,

14-3-3&[gamma] meditated transport of plakoglobin to the cellborder is required for the initiation of desmosome assembly in vitro and invivo. Journal of Cell Science

Lalit Sehgal, Amitabha Mukhopadhyay, Anandi Rajan, Nileema Khapare, Mugdha Suresh Sawant, Sonali S Vishal, Khyati Bhatt, Srikant Ambatipudi, Noelle Antao, Hunain Alam, Mansa Gurjar, Srikanta Basu, Rohit Mathur, Lalit Borde, Amol S Hosing, Milind M Vaidya,

Quantitative proteomic analysis of different stages of rat lingual carcinogenesis Clin Commun Oncol 2014, 1:2 (9 May 2014) DOI:10.4103/WKMP-0062.132172

Sharada S. Sawant, Milind M. Vaidya, Devendra A. Chaukar, Hunain Alam, Crismita Dmello, Prakash Gangadaran, Sadhana Kannan, Shubhada Kane, Prerana P. Dange, Nigamananda Dey, Ranganathan K, Animal K. D’Cruz 

Clinical significance of aberrant vimentin expression in oral premalignant lesions and carcinomas. Oral Diseases. doi:10.1111/odi.12151.

Sharada S. Sawant, Milind M. Vaidya, Devendra A. Chaukar, Hunain Alam, Crismita Dmello, Prakash Gangadaran, Sadhana Kannan, Shubhada Kane, Prerana P. Dange, Nigamananda Dey, Ranganathan K, Animal K. D’Cruz 

Understanding the Role of Keratins 8 and 18 in Neoplastic Potential of Breast Cancer Derived Cell Lines. PLOS One 8(1): e53532. Doi: 10.1371/journal.pone.0053532.

Iyer SV, Dange PP, Alam H, Sawant SS, Ingle AD, et al

Raman spectroscopic study of keratin 8 knockdown oral squamous cell carcinoma derived cells. Proc. of SPIE Vol. 8225 82251C-1

S.P.Singh, Hunain Alam, Crismita Dmello, Milind M. Vaidya, C. Murali Krishna

Alterations in keratins and associated proteins during 4- Nitroquinoline-1-oxide induced rat oral carcinogenesis. Journal of Carcinogenesis 11, 39-46.

Deepak Kanojia, Sharada S. Sawant, Anita M. Borges, Arvind D.Ingle (2012), Milind M. Vaidya

Polymeric black tea polyphenols modulate the localization and activity of 12-O-tetradecanoylphorbol-13-acetate-mediated kinases in mouse skin: Mechanisms of their anti-tumor-promoting action. Free Radical Biology and Medicine, Volume 53, Issue 6, Pages 1

Gaurav Kumar, Prerana Dange, Vaishali Kailaje, Milind M. Vaidya, Asha G. Ramchandani, Girish B. Maru, 

Plakophilin3 loss leads to an increase in PRL3 levels promoting K8 dephosphorylation, which is required for transformation and metastasis. PLoS ONE 7(6): e38561. doi:10.1371/journal.pone.0038561.

Nilima Khapare, Lalit Sehgal, Rashmi priya; Mugdha Sawant; Prajakta Satyen; Samrat Kundu; Hunain alam, Madhura Karkhanis, Nishigandha Naik, Milind Vaidya; and Sorab Dalal 

Fascin overexpression promotes neoplastic progression in oral squamous cell carcinoma. BMC Cancer, 12:32.

Hunain Alam, Amruta V Bhate, Prakash Gangadaran, Sharda S Sawant, Shimul Salot, Lalit Sehgal, Prerana P Dange, Devendra A Chaukar, Anil K D’cruz, Sadhna Kannanl, Rajiv Gude, Shubhada Kane, Sorab N Dalal, Milind M Vaidya

Loss of Keratin 8 Phosphorylation Leads to Increased Tumor Progression and Correlates with Clinico-Pathological Parameters of OSCC Patients., PLoS One. 6(11):e27767. Epub 2011 Nov 17.

Alam H, Gangadaran P, Bhate AV, Chaukar DA, Sawant SS, Tiwari R, Bobade J, Kannan S, D'cruz AK, Kane S, Vaidya MM,

Novel function of keratins 5 and 14 in proliferation and differentiation of stratified epithelial cells. Mol Biol Cell. Nov;22(21):4068-78. Epub 2011 Sep 7.

Alam H, Sehgal L, Kundu ST, Dalal SN, Vaidya MM.

Loss of keratin 8 and 18 leads to alterations in 6 4-integrin-mediated signalling and decreased neoplastic progression in an oral-tumour-derived cell line. Journal of Cell Science 124, 2096-2115.

Hunain Alam, Samrat T. Kundu, Sorab N. Dalal and Milind M. Vaidya* 

O-GlcNAcylation determines the solubility, filament organization, and stability of keratins 8 and 18. Journal of Biological Chemistry, 285 (44), pp. 34062-34071.

Srikanth, B., Vaidya, M.M., Kalraiya, R.D 

Cytokeratin fragments in the serum: Their utility for the management of oral cancer. Oral Oncol. 44(8), pp.722-732.

Sawant SS, Zingde SM, Vaidya MM

Keratins: markers of cell differentiation or regulators of cell differentiation? J Biosci. 2007 Jun;32(4):629-34.

Vaidya MM, Kanojia D.

Cytokeratin expression in oral submucous fibrosis – an Immunohistochemical study. J Oral Pathol Med.Vol 35 No 1, 25-32.

K.Ranganathan, R.Kavitha, S.S.Sawant, M.M.Vaidya

Implications of CK8 and 18 filament formation in stratified epithelial cells: induction of transformed phenotype. International Journal of Cancer, Vol.111, No.5, 662-668.

Raul UB, Sawant SS, Dange PP, Kalraiya RD and Vaidya MM. 

The database of monoclonal antibodies to cytokeratins. Oral Oncology, Vol. 40, No.3, 236-256.

Upasani OB, Bhisey AN and Vaidya MM.

Demonstration of cytokeratin-5 non-expression in tobacco related oral carcinogenesis-use of reverse transcriptase polymerase chain reaction as a sensitive assay. Oral Oncology 39:789-795.

Sawant SS, Naresh KN, D’Cruz A, Ogale SB, and Vaidya MM

Cytokeratin expression in human fetal tongue and buccal mucosa. J. Biosci. 25: 235-242.

Vaidya MM, Sawant SS, Borges AM, Naresh NK, Purandare MC and Bhisey AN.

Cytokeratin expression in precancerous lesions of the human oral cavity. Oral Oncol Eur J Cancer 34(4): 261-64.

Vaidya MM, Sawant SS, Borges AM, Ogale SB and Bhisey AN

Cytokeratin expression in squamous cell carcinomas of the tongue and alveolar mucosa. Eur. J. Cancer Oral Oncol. 32: 333-336.

Vaidya MM, Borges AM, Pradhan SA and Bhisey AN

Altered keratin expression in buccal mucosal squamous cell carcinoma. J. Oral Pathol. Med. 18: 282-286.

Vaidya MM, Borges AM, Pradhan SA, Rajpal RM and Bhisey AN