Principal Investigator
Protein synthesis (translation) is an essential process and is tightly coordinated with the cellular environment. Our research group in ACTREC is interested in exploring the novel mechanisms of regulation of protein synthesis under various growth and disease conditions. We employ both yeast and cancer cells as model systems to understand the regulation of protein synthesis by signaling pathways such as mTOR. We explore various post-translational modifications of translation factors and mRNA binding proteins and ribosome composition in the regulation of protein synthesis. In addition, we are also interested in understanding non-canonical protein synthesis mechanisms under stress conditions. We investigate peptides/proteins synthesized by non-canonical mechanisms and examine their role in cancer cells. If our research questions interest you and you want to work or collaborate with us, write to us!
Project fellow
Project fellow
PhD student
PhD student
Project fellow
Project fellow
Trainee
Trainee
Technical Assistant
Technical Assistant
Technical Assistant
Technical Assistant
PhD student
PhD student
PhD student
PhD student
Koli S, Shetty S (2024)
Shimobayashi M, Thomas A, Shetty S, Frei IC, et al.,
Shetty S, Hofstetter J, Battaglioni S, Ritz D, and Hall MN
Shetty S, and Hall MN