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Scientific Officer

Dr Syed K. Hasan

Principal Investigator

Honors and Recognitions

  • Travel grant from Society of Hematologic Oncology, Houston, USA 2018
  • European Hematology Partner Fellowship, Netherlands (2012-2014)
  • Ramalingaswami grant by DBT, Govt of India 2011
  • Pre-doctoral Fellowship, University of Rome Tor Vergata, Italy (2006-2009

Research Interests

  • Understanding the signalling between anti-apoptotic proteins and cyclin dependent kinases in Acute Myeloid Leukemia (AML) and Breast cancer.
  • Functional and molecular aspects of novel agents in leukemia, AML xenografts models
  •  Molecular characterization of high risk Acute Promyelocytic Leukemia

     

RESEARCH

Our  laboratory  is committed to unraveling  the  molecular  basis of resistance to targeted therapies in acute myeloid leukemia  and  breast cancer  employing  cancer cell lines, primary  patient  samples  and  murine models. In high-risk acute promyelocytic  leukemia, our  research  integrates  proteomics  and  single cell genomics to uncover intricate  mechanisms driving  coagulopathy  related  early  mortality  and to  identify clinically  relevant druggable targets.

Ongoing Research Projects

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    Molecular and functional characterization of small molecular inhibitor to evaluate…

    The project is focused on the elucidatio… more

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    High-risk acute promyelocytic leukemia and novel therapeutics

    The project on high-risk Acute Promyelocytic Leukemi… more

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    Harnessing the power of single-cell multiomics to uncover the complexities of acut…

    By leveraging the use of biological mate… more

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    Leveraging functional genomics and single cell profiling to delineate genetic traj…

    Acute myeloid leukemia (AML) is the deadliest of all… more

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    Deciphering the tumor-associated functions of Pregnancy Zone Protein in Breast Can…

    Pregnancy Zone Protein (PZP), a proteina… more

Lab Members

पूर्व छात्र

PUBLICATIONS

Contact

Office Contact

Dr Syed K. Hasan

KS 243, Advance Centre for Treatment Research & Education in Cancer, Tata Memorial Centre, (ACTREC), Plot No. 1 & 2, Sector 22, Kharghar, Navi Mumbai-410210. Maharashtra India. +91 (022) 2740 5000/ 6873 5000 Extn-5148 shasan@actrec.gov.in Lab Website
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