Awards

Ph.D students from Dutt Lab

Pawan Upadhyay (2011-2016)

PUBLICATIONS (only first author publications listed here)

  1. “Notch pathway activation is essential for maintenance of stem-like cells in early tongue cancer”. Upadhyay P*, Nair S*,……..Dutt A. Oncotarget. 2016 Jul 6. doi: 10.18632/oncotarget.10419. [Epub ahead of print] PubMed PMID: 27391340. (
  2. “TMC-SNPdb: an Indian germline variant database derived from whole exome sequences”. Upadhyay P, ……..Dutt A. Database (Oxford). 2016 Jul 9; 2016. pii: baw104. doi: 10.1093/database/baw104. Print 2016. PubMed PMID: 27402678.
  3. “Integrated genomics approach to identify biologically relevant alterations in fewer samples”. Chandrani, P*., Upadhyay P*., ……..Dutt A. BMC Genomics (2015), 16, 936. PubMed PMID: 26572163; PubMed Central PMCID: PMC4647579.
  4. “Mutations Are Associated with Spindle cell and Sclerosing Rhabdomyosarcomas with Aggressive Clinical Outcomes. Bharat Rekhi*, Pawan Upadhyay*,……..Dutt A. MYOD1 (L122R). Modern Pathology, 2016; DOI: 10.1038/modpathol.2016.144. PubMed PMID: 27562493”.
  5. “Applications of next-generation sequencing in cancer. Special Section: Cancer”. Upadhyay P,……..Dutt A. Current Science, September 2014, vol. 107, no. 5, 10.
  6. Genomic characterization of tobacco/nut chewing HPV-negative early stage tongue tumors identify MMP10 asa candidate to predict metastases. Upadhyay P, Gardi N, Desai S, Chandrani P, Joshi A, Dharavath B, Arora P, Bal M, Nair S, Dutt A.Oral Oncol. 2017 Oct;73:56-64.
  7. For complete list of publications of Pawan Upadhyay from Dutt lab, see here.

CONFERENCE:

  1. Upadhyay ,……..A. Dutt; OF50-003 Pro-oncogenic role of NOTCH1 in early tongue squamous cell carcinoma, New Ideas in Cancer – Challenging Dogmas (Feb 2016), Europian Journal of Cancer,10.1016/S0959-8049(16)31953-0 (ORAL PRESENTATION).
  2. Upadhyay, ……..A. Dutt; Abstract 5161: Discovery of a matrix metalloproteinase MMP10 as a clinically relevant biomarker to predict lymph node metastasis in tongue squamous cell carcinoma. Proceedings of the 106th Annual Meeting of the American Association for Cancer Research, Philadelphia, PA. USA; 04/2015. Cancer Research (International Travel award from Sam Mistry Foundation)
  3. Upadhyay, ……A. Dutt; Abstract 4811: Pro-oncogenic role of NOTCH1 in early tongue squamous cell carcinoma. AACR 106th Annual Meeting 2015, Philadelphia, USA; 08/2015. Cancer Research
  4. Upadhyay , ……..A. Dutt; P220-K020: Integrated genomics analysis of early stage tongue squamous cell carcinoma patients, New Ideas in Cancer – Challenging Dogmas (Feb 2016), Europian Journal of Cancer,10.1016/S0959-8049(16)31953-0.
  5. Chandrani , R. Prasad , A. Chougule , V. Sethunath , J. Aich , H. Dhamne , P. Upadhyay , …….A. Dutt; P49-K003: Discovery of actionable alterations in lung adenocarcinoma, New Ideas in Cancer – Challenging Dogmas (Feb 2016), Europian Journal of Cancer,10.1016/S0959-8049(16)31953-0
  6. Nair, P. Upadhyay,………Dutt A.; OP187. Early stage tongue cancer with nodal metastasis has a distinct molecular signatures. 5th World Congress of the International Academy of Oral Oncology (IAOO), Sao Paulo, Brazil; 07/2015. Head and Neck
  7. Chandrani*, P. Upadhyay*,……..Amit Dutt; Abstract C154: Integrated genomics approach to identify driver alterations. AACR-NCI-EORTC International Conference: Molecular Targets and Cancer Therapeutics, Boston, MA; 11/2015. Molecular cancer therapeutics
  8. Prabhash, P. Chandrani, J. Agich, P. Upadhyay,……A. Dutt; Profiling of actionable alterations in lung adenocarcinoma, JOURNAL OF THORACIC ONCOLOGY (S1261- S1261) 2013.
  9. Nair, P. Upadhyay,…..A. Dutt; Abstract C125: Development of gene signature profile predicting nodal metastasis in squamous cell carcinoma of tongue.. AACR-NCIEORTC International Conference: Molecular Targets and Cancer Therapeutics, Boston, MA. Philadelphia; 10/2013, Molecular cancer therapeutics

AWARDS:

  1. International Travel award from Sam Mistry Foundation, Mumbai, India; 2015 (AACR meeting, USA)
  2. Best poster award in Second “Global cancer genomics consortium-2012” conference; 2012

 

Pratik Chandrani (2011-2017)

PUBLICATIONS (only first author publications listed here)

  1. Chandrani P*, Prabhash K.*, Choughule A, Prasad R, Sethunath V, Ranjan M, Aich J, Dhamne H, Iyer D, Upadhyay P, Sundaram P, Mohanty B, Chandna P, Kumar R, Joshi A, Noronha V, Patil V, Ramaswamy A, Karpe A, Thorat R, Chaudhary P, Ingle A, Dutt A. Drug-sensitive FGFR3 mutations in lung adenocarcinoma. Annals of Oncology. 2016 Dec 19. pii: mdw636. doi: 10.1093/annonc/mdw636. PubMed PMID: 27998968 [Epub ahead of print].
  2. Chandrani P*, Upadhyay P*, Iyer P, Tanna M, Shetty M, Raghuram GV, Oak N, Singh A, Chaubal R, Ramteke M, Gupta S, Dutt A. Integrated genomics approach to identify biologically relevant alterations in fewer samples. BMC Genomics. 2015 Nov 14;16(1):936. doi: 10.1186/s12864-015-2138-4. PubMed PMID: 26572163; PubMed Central PMCID: PMC4647579.
  3. Chandrani P*, Kulkarni V*, Iyer P, Upadhyay P, Chaubal R, Das P, Mulherkar R, Singh R, Dutt A. NGS-based approach to determine the presence of HPV and their sites of integration in human cancer genome. Br J Cancer. 2015 Jun 9;112(12):1958-65. doi: 10.1038/bjc.2015.121. Epub 2015 May 14. PubMed PMID: 25973533; PubMed Central PMCID: PMC4580395.
  4. Chandrani P and Dutt A. Domain Specific Targeting of Cancer. in Nuclear Signalling Pathways and Targeting Transcription in Cancer 299-310 (Springer, 2014).
  5. For complete list of publications of Pratik Chandrani from Dutt lab, see here.

CONFERENCE AND AWARDS:

  1. P Chandrani, V Sethunath, A Chougule, J Aich, H Dhamne, P Upadhyay, D N Iyer, A Thavamani, R Sindhi, P Chandna, K Prabhash and A Dutt. Discovery of Actionable Alterations in Lung Adenocarcinoma poster presentation at “Conference - Decoding the Genetics of Common Cancers in India”, 19-21 February, 2016 in Pune, India. (recipient of first prize)
  2. P Chandrani, V Sethunath, A Chougule, J Aich, H Dhamne, P Upadhyay, D N Iyer, A Thavamani, R Sindhi, P Chandna, K Prabhash and A Dutt. Discovery of Actionable Alterations in Lung Adenocarcinoma poster presentation at “A Conference of New Ideas in Cancer – Challenging Dogmas”, 26-28 February, 2016 in Mumbai, India. (recipient of third prize)
  3. P Chandrani, Pawan Upadhyay, Prajish Iyer, Mayur Tanna, Madhur Shetty, Raghuram Venkata Gorantala, Ninad Oak, Ankita Singh, Rohan Chaubal, Manoj Ramteke, Sudeep Gupta, Amit Dutt. Integrated genomics approach to identify driver alterations. [abstract]. In: Proceedings of the AACR-NCI-EORTC International Conference: Molecular Targets and Cancer Therapeutics; 2015 Nov 5-9; Boston, MA. Philadelphia (PA): AACR; Mol Cancer Ther 2015;14(12 Suppl 2): Abstract nr C154.
  4. P Chandrani, V Sethunath, A Chougule, J Aich, H Dhamne, P Upadhyay, D N Iyer, A Thavamani, R Sindhi, P Chandna, K Prabhash and A Dutt. Discovery of Actionable Alterations in Lung Adenocarcinoma oral presentation at “34th Annual Convention of Indian Association for Cancer Research”, 19-21 February, 2015 in Jaipur, India. (selected in top abstracts for oral presentation under IACR Sitaram Joglekar award and Mangala Bamne award category)
  5. P Chandrani, P Iyer, V Kulkarni, P Upadhyay, R Chaubal, P Das, R Mulherkar, R Singh, A Dutt. HPVDetector: A Tool to Detect HPV and Their Integration Sites Using Next Generation Sequencing Data poster presentation by P Iyer at “NextGen Genomics & Bioinformatics Technologies (NGBT) Conference”, 17-19 November, 2014 in Bangalore, India. (recipient of first prize)
  6. P Chandrani, Aich J, Upadhyay P, Chougule A, Jose T, Chandna P, Prabhash K, Dutt A. Profiling and Discovery of Actionable Alterations in Lung Adenocarcinoma poster presentation at “Worldwide Innovative Networking (WIN-2013)”, 10-12 July, 2013 in Paris, France.
  7. P Chandrani, Iyer D, Aich J, Upadhyay P, Chougule A, Jose T, Chandna P, Prabhash K, Dutt A. Profiling and Discovery of Actionable Alterations in Lung Adenocarcinoma poster presentation at “Integrating Basic and Translational Research in Modern Biology”, 27-28 December, 2013 in Vadodara, India.
  8. P Chandrani, Prasad R, Upadhyay P, Thavamani A, Trivedi V, Sharma R, Chougule A, Jambhekar N, Noronha V, Jose T, Prabhash K, Dutt A. Mutational Profiling of Actionable Alterations in Lung Adenocarcinoma poster presentation at “2nd Global Cancer Genomics Consortium Symposium: Genomics Medicine in Cancer Research”, 19-20 November, 2012 in Mumbai, India. (recipient of best poster presentation award)

 

Prajish Iyer (2012-2017)

PUBLICATIONS (only first author publications listed here)

  1. Iyer P, Barreto SG, Sahoo B, Chandrani P, Ramadwar MR, Shrikhande SV, Dutt A. Non-typhoidal Salmonella DNA traces in gallbladder cancer. Infectious agents and cancer. 2016; 11:12.
  2. Iyer P, Shrikhande SV, Ranjan M, Joshi A, Gardi N, Prasad R, Dharavath B, Thorat R, Salunkhe S, Sahoo B, Chandrani P, Kore H, Mohanty B, Chaudhari V, Choughule A, Kawle D, Chaudhari P, Ingle A, Banavali S, Gera P, Ramadwar MR, Prabhash K, Barreto SG, Dutt S, Dutt A. ERBB2 and KRAS alterations mediate response to EGFR inhibitors in early stage gallbladder cancer. Int J Cancer. 2019 Apr 15;144(8):2008-2019
  3. For complete list of publications of Prajish Iyer from Dutt lab, see here.

CONFERENCE AND AWARDS:

  1. Iyer, N.Gardi, M.Ranjan, Bikram Sahoo, P.Chandrani, P.Upadhyay, M.R.Ramadwar, S.V.Shrikhande, A.Dutt Abstract 4397: Deciphering the Diversity of Somatic Alterations and Salmonella Infection in Gallbladder Cancer by Whole Exome Sequencing (April 1st – 5th, 2017) Proceedings of the 108th Annual Meeting of the American Association for Cancer Research, Washington D.C(Poster Presentation).
  2. Iyer, N.Gardi, M.Ranjan, P.Chandrani, P.Upadhyay, M.R.Ramadwar, S.V.Shrikhande, A.Dutt Abstract K002: Discovery of somatic ERBB2 alterations in human  gallbladder cancer  New Ideas in Cancer – Challenging Dogmas (26th- 28th Feb 2016), European Journal of Cancer,10.1016/S0959-8049(16)31953-0 (Poster Presentation)
  3. Iyer, N.Gardi, M.Ranjan, Bikram Sahoo,P.Chandrani, P.Upadhyay, M.R.Ramadwar, S.V.Shrikhande, A.Dutt Deciphering the Diversity of Somatic Alterations and Salmonella Infection in Gallbladder Cancer by Whole Exome Sequencing (April 8th – 10th, 2016) 35th Annual Convention of Indian Association for Cancer Research (Oral Presentation under award category)
  4. Iyer, N.Gardi, M.Ranjan, Bikram Sahoo, P.Chandrani, P.Upadhyay, M.R.Ramadwar, S.V.Shrikhande, A.Dutt Landscape of somatic alterations and identification of non-typhoidal Salmonella traces in gallbladder cancer (January 29th – 30th 2016) MOSCON conference. (Poster Presentation)
  5. Iyer, N.Gardi, M.Ranjan, Bikram Sahoo, P.Chandrani, P.Upadhyay, M.R.Ramadwar, S.V.Shrikhande, A.Dutt Deciphering the Diversity of Somatic Alterations and Salmonella Infection in Gallbladder Cancer by Whole Exome Sequencing (October 3rd - 5th, 2016) 2016 NextGen Genomics and Bioinformatics (Nature reviews Best Poster award)
  6. Iyer, N.Gardi, M.Ranjan, Bikram Sahoo, P.Chandrani, P.Upadhyay, M.R.Ramadwar, S.V.Shrikhande, A.Dutt Deciphering the Diversity of Somatic Alterations and Salmonella Infection in Gallbladder Cancer by Whole Exome Sequencing (December 7th – 11th, 2016) India International Science Festival (Poster Presentation)-Selected among 8000 posters in the Life science category

 

Mukul Godbole (2012-2017)

PUBLICATIONS (only first author publications listed here)

  1. “Progesterone suppresses the invasion and migration of breast cancer cells irrespective of their progesterone receptor status – a short report.”, Godbole M, Tiwary K, Badwe R, Gupta S, Dutt A, Cellular Oncology (Dordr), 2017, 40(4): 411-417. PMID: 28653288.
  2. “miR-129-2 mediates down-regulation of progesterone receptor in response to progesterone in breast cancer cells”, Godbole M, Chandrani P, Gardi N, Dhamne H, Patel K, Yadav N, Gupta S, Badwe R, Dutt A, Cancer Biology & Therapy, 2017, 18(10): 801-805. PMID: 28876975
  3. Up-regulation of the kinase gene SGK1by progesterone activates the AP-1-NDRG1 axis in both PR-positive and -negative breast cancer cells. Godbole M, Togar T, Patel K, Dharavath B, Yadav N, Janjuha S, Gardi N, Tiwary K, Terwadkar P, Desai S, Prasad R, Dhamne H, Karve K, Salunkhe S, Kawle D, Chandrani P, Dutt S, Gupta S, Badwe RA, Dutt A. J Biol Chem. 2018 Dec 14;293(50):19263-19276.
  4. For complete list of publications of Mukul Godbole from Dutt lab, see here.

CONFERENCE AND AWARDS:

  1. M Godbole, K Tiwary, N Gardi, K Patel, R Chaubal, K Karve, V Parmar, N Nair, S Gupta, R Badwe, A Dutt. Progesterone Suppresses Breast Cancer Invasion and Migration by Up-regulating a Serine/Threonine Protein Kinase SGK1; ENZYMES Conference, ACTREC (2017) (Poster presentation).
  2. M Godbole, K Tiwary, N Gardi, K Patel, R Chaubal, K Karve, V Parmar, N Nair, S Gupta, R Badwe, A Dutt. Progesterone up-regulates and activates a tumor metastasis suppressor gene NDRG1 in human breast cancer cells; All India Cell Biology Conference (AICBC), Gwalior (2016) (Poster presentation)
  3. M Godbole, R Badwe, N Gardi, K Patel, K Tiwary, R Chaubal, K Karve, V Parmar, N Nair, S Gupta, A Dutt. Progesterone up-regulates and activates a tumor metastasis suppressor gene NDRG1 in human breast cancer cells; Tata Memorial Centre Platinum Jubilee, A conference of new ideas in cancer—challenging dogmas (2016) (Poster presentation).
  4. M Godbole, P Chandrani, H Dhamne, K Patel, N Gardi, K Tiwary, S Gupta, R Badwe, A Dutt. Dual Regulatory Model for Regulation of SGK1 by Progesterone in Human Breast Cancer Cells; Tata Memorial Centre Platinum Jubilee, A conference of new ideas in cancer—challenging dogmas (2016) (Poster presentation).
  5. M Godbole, K Patel, N Gardi, R Chaubal, K Karve, V Trivedi, V Parmar, N Nair, S Gupta, R Badwe, A Dutt. Progesterone up-regulates NDRG1, a tumor suppressor gene, in human breast cancer cells; MOSCon Pune (2016) (Poster presentation).
  6. M Godbole, K Patel, N Gardi, R Chaubal, K Karve, V Trivedi, V Parmar, N Nair, S Gupta, R Badwe, A Dutt. Progesterone up-regulates NDRG1, a tumor suppressor gene, in human breast cancer cells; 34th Annual Convention of Indian Association for Cancer Research (IACR), Jaipur (2015) (Poster presentation).

 

Trupti Togar (2014-2020)

PUBLICATIONS (only first author publications listed here)

  1. Togar, T., Desai, S., Mishra, R., Terwadkar, P., Ramteke, M., Ranjan, M., . . . Dutt, A. (2020). Identifying cancer driver genes from functional genomics screens. Swiss Med Wkly, 150, w20195. doi:10.4414/smw.2020.20195
  2. For complete list of publications of Trupti Togar from Dutt lab, see here.

CONFERENCE:

  1. Togar, S Chopra, S Desai, N Gardi, B Dharavath, B Sahoo, H Kore, S Gupta, A Dutt: Genomic Characterization of Somatic Alterations in Cervical Adenocarcinoma, 4th EACR conference- Cancer Genomics (2019), Cambridge, UK (Poster presentation)
  2. Togar, S Chopra, S Desai, N Gardi, B Dharavath, B Sahoo, H Kore, S Gupta, A Dutt: Genomic Characterization of Somatic Alterations in Cervical Cancer, NGBT conference (2018), Jaipur, India. (Poster presentation)
  3. Togar, S Chopra, N Gardi, B Dharavath, B Sahoo, H Kore, S Gupta, A Dutt: Genomic Characterization of Somatic Alterations in Cervical Cancer,37th IACR Convention (2018), Kolkata, India. (Poster presentation)
  4. Togar, N Gardi, B Sahoo, P Upadhyay, S Chopra, A Dutt: Genomic Characterization of Somatic Alterations in Cervical Adenocarcinoma, NGBT conference (2016), Cochin, India. (Poster presentation)
  5. Togar, N Gardi, P Upadhyay, S Chopra, A Dutt: Genomic Characterization of Somatic Alterations in Cervical Adenocarcinoma, Tata Memorial Centre Platinum Jubilee Conference (2016) in Mumbai, India. (Poster presentation)
  6. Togar, N Gardi, P Upadhyay, S Chopra, A Dutt: Genomic Characterization of Somatic Alterations in Cervical Adenocarcinoma ,1st MOSCON conference (2016), Pune, India. (Poster presentation)

AWARDS

  1. Won best poster award at MOSCON conference, 2015
  1. NGBT YUVA Scholarship award for poster presentation at NGBT conference, Jaipur, 2018

 

Sanket Desai (2015-2022)

PUBLICATIONS (only first author publications listed here)

  1. Desai S.*, Mishra R*, Ahmed S., Hait S., Joshi A., Dutt A. TMC-SNPdb 2.0: an ethnicspecific database of Indian germline variants. Database, 2022; Volume 2022, 2022, baac029.
  2. Desai S., Dharavath B., Manavalan S., Rane A., Redhu AK., Sunder R., Butle A., Mishra R., Joshi A., Togar T., Apte S., Bala P., Chandrani P., Chopra S., Bashyam MD., Banerjee A., Prabhash K., Nair S., Dutt A. Fusobacterium nucleatum is associated with inflammation and poor survival in early-stage HPV-negative tongue cancer. NAR Cancer, 2022; Volume 4, Issue 1, March 2022, zcac006.
  3. Desai S., Rashmi S, Rane A, Dharavath B, Sawant A, Dutt A. An integrated approach to determine the abundance, mutation rate and phylogeny of the SARS-CoV-2 genome. Briefings In Bioinformatics, 2021; 22(2), 2021, 1065–1075.
  4. Desai S.*, Mishra S*, Joshi A*, Sarkar D, Hole A, Mishra R, Dutt S, Chilakapati M.K., Gupta S, Dutt A. Raman spectroscopy-based detection of RNA viruses in saliva: a preliminary report. Journal of Biophotonics, 2020;13(10).
  5. Desai S., Rane A., Joshi A., Dutt A. IPD 2.0: To derive insights from an evolving SARS CoV-2 genome. BMC Bioinformatics, 2021; 22:247.
  6. For complete list of publications of Sanket Desai from Dutt lab, see here.

CONFERENCE AND AWARDS:

  1. Presented poster at the 41st Indian Association for Cancer Research (IACR-2022)
  2. 2nd runner up prize at 8th national annual conference, Indian Society of Medical and Pediatric Oncology (ISMPOCON 2022)
  3. Presented poster at 28th Intelligent Systems for Molecular Biology (virtual conference), (ISMB-2020)
  4. Participated as Tutor, at 2nd UK-India Cancer Informatics Workshop (2019), at ACTREC, India
  5. Best Poster Award, Molecular Pathology Association of India, Conference (2019), Navi Mumbai, India
  6. Oral presentation at the Indian Association of Cancer Research, Conference 2019, Chandigarh, India
  7. Participated as Tutor, at one day NGS data analysis workshop, organized by Indian Association of Cancer Research (2019), Chandigarh, India
  8. Participated as Tutor, at UK-India Cancer Informatics Workshop (2018), held at ACTREC, India ­­
  9. Poster presentation at NextGen Genomics, Biology, Bioinformatics and Technologies (NGBT) Conference, 2017, Bhubaneshwar, Odisha
  10. Participated as Tutor at 'Genomic Applications in Healthcare and Translational Research' workshop 2017, under the aegis of the B4 (Bangalore-Boston Biosciences Beginnings') program, held at IBAB, Bangalore
  11. Poster presentation in Indo-US Conference on Advances in Enzymology: Implications in Health, Disease and Therapeutics (Enzymes 2017), Navi MumbaiJoshi A, Butle A, Hait S, Mishra R, Trivedi V, Choughule A, Noronha V, Prabhash K, Dutt A, Osimertinib, a 3rd generation EGFR-TKI, is a viable therapeutic option for lung cancer patients harboring low allele frequency EGFR T790M mutation, 41st Annual Convention of Indian Association of Cancer Research (IACR 2022), Amity University, Noida, India. (Oral presentation)

 

Asim Joshi (2015-2022)

PUBLICATIONS (only first author publications listed here)

  1. Joshi A, Mishra R, Desai S, Chandrani P, Kore H, Sunder R, Hait S, Iyer P, Trivedi V, Choughule A, Noronha V, Joshi A, Patil V, Menon N, Kumar R, Prabhash K, Dutt A. Molecular characterization of lung squamous cell carcinoma tumors reveals therapeutically relevant alterations. Oncotarget. 2021 Mar 16;12(6):578-588. doi: 10.18632/oncotarget.27905.
  2. Butle A*, Joshi A*, Noronha V, Prabhash K, Dutt A. Weekly osimertinib dosing prevents EGFR mutant tumor cells destined to home mouse lungs. Translational Oncology. 2021 Aug;14(8):101111. doi: 10.1016/j.tranon.2021.101111.
  3. Joshi A*, Butle A*, Hait S, Mishra R, Trivedi V, Thorat R, Choughule A, Noronha V, Prabhash K, Dutt A. Osimertinib for lung cancer cells harboring low allele frequency EGFR T790M mutation. Translational Oncology. 2022 May 30;22:101461. doi: 10.1016/j.tranon.2022.101461.
  4. Desai S*, Mishra SV*, Joshi A*, Sarkar D, Hole A, Mishra R, Dutt S, Chilakapati MK, Gupta S, Dutt A. Raman spectroscopy-based detection of RNA viruses in saliva: a preliminary report. Journal of Biophotonics. 2020 Oct;13(10):e202000189. doi: 10.1002/jbio.202000189.
  5. For complete list of publications of Asim Joshi from Dutt lab, see here.

CONFERENCE AND AWARDS:

  1. Joshi A, Butle A, Hait S, Mishra R, Trivedi V, Choughule A, Noronha V, Prabhash K, Dutt A, Osimertinib, a 3rd generation EGFR-TKI, is a viable therapeutic option for lung cancer patients harboring low allele frequency EGFR T790M mutation, 41st Annual Convention of Indian Association of Cancer Research (IACR 2022), Amity University, Noida, India. (Oral presentation)
  2. Joshi A, Butle A, Noronha V, Prabhash K, Dutt A, Efficacy of Weekly Dosing over Daily Dosing: A Comparable Response Using a Mouse Model for the ADAURA Clinical Trial, Indian Society of Medical and Pediatric Oncology Conference, India (1st Runner-up of the Translational Science Oral Presentation Competition)
  3. Joshi A*, Butle A*, Noronha V, Prabhash K, Dutt A, EGFR-TKI Pretreatment Prevents the Emergence of EGFR-mutant Lung Tumors in Mice, OFCON 2020, Virtual Conference, India (poster presentation)
  4. Butle A*, Joshi A*, Thorat R, Noronha V, Prabhash K, Dutt A, An Orthotopic Mice Model for Lung Cancer Closely Recapitulates Clinical Disease in NOD-SCID Mice, OFCON 2020 Virtual Conference, India (best poster award)
  5. Joshi A, Choughule A, Kore H, Chandrani P, Hait S, Trivedi V, Prabhash K, Dutt A, Elucidating the Mechanisms of Resistance to EGFR Tyrosine Kinase Inhibitors in Lung Cancer Patients, 38th Annual Convention of Indian Association of Cancer Research (IACR), 2019, Chandigarh, India (Poster Presentation, awarded the Rajnikant Baxi award)
  6. Joshi A, Choughule A, Chandrani P, Trivedi V, Iyer P, Prabhash K, Dutt A, Elucidating the Mechanisms of Resistance to Tyrosine Kinase Inhibitors in Lung Cancer Patients, Molecular Pathology Association of India (MPAI) Conference, 2019, ACTREC-TMC, Navi Mumbai, Maharashtra, India (Poster Presentation)
  7. Joshi A, Choughule A, Chandrani P, Trivedi V, Iyer P, Prabhash K, Dutt A, Elucidating the Mechanisms of Resistance to Tyrosine Kinase Inhibitors in Lung Cancer Patients, NextGen Genomics, Biology, Bioinformatics and Technologies (NGBT) Conference, 2017, Odisha, India (Poster Presentation)

 

Neelima Yadav (Viva voce awaited)

PUBLICATIONS (only first author publications listed here)

  1. Yadav N, Sunder R, Desai S, Dharavath B, Chandrani P, Godbole M, Dutt A. Progesterone modulates the DSCAM-AS1/miR-130a/ESR1 axis to suppress cell invasion and migration in breast cancer. Breast Cancer Research, 2022 Dec. doi: 10.1186/s13058-022-01597-x, PMID: 36578092
  2. For complete list of publications of Neelima Yadav from Dutt lab, see here.

 

CONFERENCE AND AWARDS:

  1. Yadav N, Sunder R, Desai S, Dharavath B, Chandrani P, Dutt A. “Progesterone modulates DSCAM-AS1/miR-130a/ESR1 axis to suppress invasion and migration in breast cancer” at the Indian Association for Cancer Research (IACR-2023), Navi Mumbai, India (Best poster presentation award).
  2. Yadav N, Sunder R, Desai S, Dharavath B, Chandrani P, Godbole M, Dutt A. “Progesterone modulates DSCAM-AS1/miR-130a/ESR1 axis to suppress invasion and migration in breast cancer” at the National Research Scholar Meet (NRSM-2022), Navi Mumbai, India (Oral presentation).
  3. Yadav N, Sunder R, Desai S, Chandrani P, Dutt A. “Progesterone modulates DSCAMAS1/miR-130a/ESR1 axis to suppress invasion and migration in breast cancer” at the European Association for Cancer Research Congress (EACR-2022), Seville, Spain (Poster presentation).
  4. Yadav N, Sunder R, Desai S, Chandrani P, Dutt A. “Progesterone modulates DSCAMAS1/miR-130a/ESR1 axis to suppress invasion and migration in breast cancer” at the 41st Indian Association for Cancer Research conference (IACR-2022), Noida, India. (Amity best oral presentation award)
  5. Yadav N, Sunder R, Desai S, Chandrani P, Dutt A. “Progesterone modulates DSCAMAS1/miR-130a/ESR1 axis to suppress invasion and migration in breast cancer” at the 8 th national annual conference, Indian Society of Medical and Pediatric Oncology (ISMPOCON 2022) (Poster presentation).
  6. Yadav N, Varhadi S, Rashmi S, Chandrani P, Desai S, Dutt A. “Characterization of long non-coding RNAs deregulated by progesterone in human breast cancer cells” at the 39th Indian Association of Cancer Research Conference (IACR-2020), Kerala, India (Poster presentation).
  7. Yadav N, Chandrani P, Desai S, Godbole M, Gupta S, Badwe R, Dutt A. “Characterization of long non-coding RNAs deregulated by progesterone in human breast cancer cells” at the 38th Indian Association of Cancer Research Conference (IACR-2019), Chandigarh, India (Poster presentation).
  8. Yadav N, Chandrani P, Godbole M, Desai S, Gupta S, Badwe R, Dutt A. “Role of progesterone in regulating long non-coding RNAs of human breast cancer cells” at Molecular Pathology Association of India Conference (MPAI-2019), Navi Mumbai, India (Poster presentation).

 

Bhasker Dharavath (Viva voce awaited)

PUBLICATIONS (only first author publications listed here)

  1. Dharavath B, Butle A, Pal A, Desai S, Upadhyay P, Rane A, Khandelwal R, Manavalan S, Thorat R, Sonawane K, Vaish R, Gera P, Bal M, D’Cruz AK, Nair S, Dutt A. Role of miR-944/MMP10/AXL- axis in lymph node metastasis in tongue cancer, Communications Biology (2023); doi: 10.1038/s42003-023-04437-6.
  2. Dharavath B*, Yadav N*, Desai S*, Sunder R, Mishra R, Ketkar M, Bhanshe P, Gupta A, Redhu AK, Patkar N, Dutt S, Gupta S, Dutt A. A one-step, one-tube real-time RT-PCR based assay with an automated analysis for detection of SARS-CoV-2 Heliyon 6 (2020) e04405. doi: 10.1016/j.heliyon.2020.e04405.
  3. For complete list of publications of Bhasker Dharavath from Dutt lab, see here.

CONFERENCE

  1. Dharavath B, Butle A, Pal A, Desai S, Upadhyay P, Rane A, Khandelwal R, Manavalan S, Thorat R, Sonawane K, Vaish R, Gera P, Bal M, D’Cruz AK, Nair S, Dutt A. “Role of miR-944/MMP10/AXL- axis in lymph node metastasis in tongue cancer”, at the 42nd Indian Association for Cancer Research (IACR-2023), Navi Mumbai, India (Oral Presentation).
  2. Dharavath B, Butle A, Pal A, Desai S, Upadhyay P, Rane A, Khandelwal R, Manavalan S, Thorat R, Sonawane K, Vaish R, Gera P, Bal M, D’Cruz AK, Nair S, Dutt A. “Role of miR-944/MMP10/AXL- axis in lymph node metastasis in tongue cancer”, at the National Research Scholar Meet (NRSM-2022), Navi Mumbai, India (Best Oral Presentation Award).
  3. Dharavath B, Butle A, Pal A, Desai S, Upadhyay P, Gera P, Bal M, D’Cruz AK, Nair S, Dutt A. “miR-944/MMP10/AXL- axis Predict Lymph Node Metastasis in Early Stage Tongue Cancer”, at the European Association for Cancer Research Congress (EACR-2022), Seville, Spain (Poster Presentation).
  4. Dharavath B, Butle A, Pal A, Desai S, Upadhyay P, Rane A, Khandelwal R, Manavalan S, Thorat R, Sonawane K, Vaish R, Gera P, Bal M, D’Cruz AK, Nair S, Dutt A. “miR-944/MMP10/AXL- axis Predict Lymph Node Metastasis in Early Stage Tongue Cancer”, at the 41st Indian Association for Cancer Research (IACR-2022), Noida, India (Sitaram Joglekar Award for Best Oral Presentation).
  5. Dharavath B, Butle A, Pal A, Desai S, Upadhyay P, Rane A, Khandelwal R, Manavalan S, Thorat R, Sonawane K, Vaish R, Gera P, Bal M, D’Cruz AK, Nair S, Dutt A. “miR-944/MMP10/AXL- axis Predict Lymph Node Metastasis in Early Stage Tongue Cancer”, at the 8th Indian Society of Medical and Pediatric Oncology (ISMPOCON-2022) (Winner of the Translational Science Oral Presentation Competition).
  6. Dharavath B, Manavalan S, Bal M, Upadhyay P, Gardi N, Nair S, Dutt A. “Identification and characterization of potential biomarkers to predict metastasis in early stage tongue cancer”, at the 39th Indian Association for Cancer Research (IACR-2020), Kerala, India (Poster Presentation).
  7. Dharavath B, Bal M, Upadhyay P, Gardi N, D’Cruz AK, Nair S, Dutt A. “Identification and characterization of potential biomarkers to predict metastasis in early stage tongue cancer”, at the 38thIndian Association for Cancer Research (IACR-2019), Chandigarh, India (Poster Presentation, received travel grant).
  8. Upadhyay P, Dharavath B, Desai S, Terwadkar P, Chaubal R, Joshi A, Nair S, Dutt A. “Integrated Genomic Analysis of Early Stage Tongue Tumors Revealed Recurrent Transcript Fusions”, at the Molecular Pathology Association of India Conference (MPAI-2019), Navi Mumbai, India(Poster Presentation).
  9. Upadhyay P, Desai S, Dharavath B, Joshi A, Terwadkar P, Nair S, Dutt A. “Integrated Genomic Analysis of Early Stage Tongue Tumors Revealed Recurrent Transcript Fusions”, at the NextGen Genomics, Biology, Bioinformatics and Technologies (NGBT-2017), Odisha, India (Poster Presentation).

AWARDS AND RECOGNITION:

  1. Best Oral Presentation Award at the National Research Scholar Meet (NRSM-2022), Navi Mumbai, India
  2. Sitaram Joglekar Award for Best Oral Presentation at the 41st Indian Association of Cancer Research (IACR-2022), Noida, India
  3. Winner of the Translational Science Oral Presentation Competition at the 8th Indian Society of Medical and Pediatric Oncology Conference (ISMPOCON-2022), India
  4. SERB-International Travel Scheme (ITS) grant for presenting a poster at the international conference "European Association for Cancer Research Congress (EACR-2022)", Seville, Spain
  5. Travel Grant for poster presentation at the 38th Indian Association of Cancer Research (IACR 2019), Chandigarh, India
  6. Biopatrika, Author Interview– “Novel Biomarker for predicting the spread of Tongue cancer”, 24th April, 2023.
  7. The Indian Express, Health and Wellness– “Tata Memorial develops novel biomarker for tongue cancer spread to spare 70% patients from neck surgery”, 5th February, 2023.
  8. Nature Portfolio Cancer Community, Behind the Paper– “miR-944/MMP10/AXL- axis Predict Metastasis in Tongue Cancer”, 17th January, 2023.
  9. Scisoup, Science blog– “A Blueprint To Develop A Rapid qRT-PCR kit To Detect SARS-CoV-2: Study”, 13th July, 2020.
  10. Regular Reviewer for Heliyon (March 2022-Present).

 

Supriya Hait

CONFERENCE

  1. Hait S, Choughule A, Joshi A, Chandrani P, Mishra R, Prabhash K, Dutt A. “An Integrative Approach to Understand Resistance to ALK Tyrosine Kinase Inhibitor in Human Lung Cancer ”, at the National Research Scholar Meet (NRSM-2019), Navi Mumbai, India (Poster Presentation).
  2. Hait S, Choughule A, Joshi A, Chandrani P, Mishra R, Prabhash K, Dutt A. “An Integrative Approach to Understand Resistance to ALK Tyrosine Kinase Inhibitor in Human Lung Cancer ”, at the 38thIndian Association for Cancer Research (IACR-2019), Chandigarh, India (Poster Presentation).

 

Dr. Kuldeep Patel

CONFERENCE AND AWARDS:

  1. Kuldeep Patel, Integrated Genomics Approach to Identify the Transcriptional Targets of Progesterone in Human Breast Cancer, 2013, 32nd Annual Convention of Indian Association for Cancer Research (IACR) "Emerging Trends in Cancer Research: Road to Prevention & Cure" International Symposium on: Infection & Cancer) (Young Scientist Award).

 

Rohan Chaubal

CONFERENCE AND AWARDS:

  1. Rohan Chaubal, Computational subtraction to determine traces of human genetic material from NIH3T3 cells transformed by chromatin and DNA fragments extracted from cancer patients, 2012, The Global Cancer Genomics Consortium Second Annual Symposium: Genomics Medicine in Cancer Research, (Best poster award).

 

Vaishakhi Trivedi

CONFERENCE AND AWARDS:

  1. Vaishakhi Trivedi, S Basu, H Kore, N Singh, D Nemne, K Nambiar, N Neman, A Choughule, V Noronha, A Joshi, V Patil, A Dutt and K Prabhash.Genomic profiling of papillary thyroid cancer.(24th – 26th August, 2018),3rd National meeting of the Indian Society of Thyroid Surgeons (Awarded first prize).
  2. Vaishakhi Trivedi, S Basu, H Kore, N Singh, D Nemne, K Nambiar, N Neman, A Choughule, V Noronha, A Joshi, V Patil, A Dutt and K Prabhash.Genomic profiling of papillary thyroid cancer.(4th – 26th August, 2018),ISMPOCON – Conquering cancer – current concepts. (Awarded first prize).

 

 


Postdocs from Dutt Lab

Ashwin Butle(2019-Present)

PUBLICATIONS (only first author publications listed here)

  1. Joshi A , Butle A, Hait S, Mishra R, Trivedi V, Thorat R, Choughule A, Noronha V, Prabhash K, Dutt A. Osimertinib for lung cancer cells harboring low-frequency EGFR T790M mutation. Transl Oncol. 2022 Aug;22:101461. doi: 10.1016/j.tranon.2022.101461. Epub 2022 May 30. PMID:35653897; PMCID: PMC9156817.
  2. Butle A, Joshi A, Noronha V, Prabhash K, Dutt A. Weekly osimertinib dosing prevents EGFR mutant tumor cells destined to home mouse lungs. Transl Oncol. 2021 Aug;14(8):101111. doi: 10.1016/j.tranon.2021.101111. Epub 2021 May 13. PMID: 33993094; PMCID: PMC8236545.
  3. For complete list of publications of Ashwin Butle from Dutt lab, see here.

CONFERENCE AND AWARDS:

  1. National Postdoctoral Fellowship (NPDF) from Science and Engineering Research Board (SERB), Department of Science and Technology, India, May 2022.
  2. Ad-hoc Scientific Officer, position bestowed from Director ACTREC, TMC, Navi-Mumbai,November 2022
  1. Abstract, 2021 ASCO Annual Meeting I, Butle A , Joshi A, Noronha V, Prabhash K, Dutt A.Weekly osimertinib dosing to prevent EGFR mutant tumor cells destined to home mouse lungs. Journal of Clinical Oncology 2021 39:15_suppl, e20504-e20504.
  1. Best Poster presentation, ‘An orthotopic mouse model for lung cancer closely recapitulates clinical disease in NOD-SCID mice to study TKI resistance’, at Annual Conference on Oncology Forum (OFCON-2020), December 2020.
  2. Institutional Postdoctoral Fellowship, Advanced Centre for Treatment, Research and Education in Cancer (ACTREC), Navi-Mumbai, August 2019.

Archana Redhu(2020-Present)

PUBLICATIONS

  1. Fusobacterium nucleatum is associated with inflammation and poor survival in early-stage HPV-negative tongue cancer.  Sanket Desai et al., NAR Cancer. 2022 Mar; 4(1): zcac006.
  2. A one-step, one-tube real-time RT-PCR based assay with an automated analysis for detection of SARS-CoV-2. Dharavath B et al., Heliyon .2020 Jul 7;6(7) :e04405

CONFERENCE AND AWARDS:

  1. Awarded by DBT-Research Associate (RA) fellowship in 2021.