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Advanced Centre for Treatment Research & Education in Cancer
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Science Sparks @ ACTREC
Date Image06 April 2026 Vol. No. 15 ; Issue No.729
Publications

1. Noronha V, Sarkar L, Pillai A, Rao AR, Kumar A, Dhekale R, Mahajan S, Daptardar A, Sonkusare L, Vagal M, Mahajan P, Timmanpyati S, Gota V, Laskar S, Budrukar A, Swain M, Shetake A, Chowdhury OR, Pawar A, Prabhash K . Vulnerability assessment and decision-making in older patients with head and neck cancers planned for chemoradiation: Experience from a Tertiary Care Cancer Centre in India. Journal of Cancer Research and Therapeutics. 22(1):168-174

2. Chakrabarty N, Dadlani T, Mahajan A, Laskar SG, Nair D, Menon M, Rane S, Rane P, Deshmukh A, Pantvaidya G, Singh A, Sahu A, Patil A, Noronha V, Prabhash K, Chaturvedi P (2026). Diagnostic value of MRI-based iENE assessment for predicting major and minor extranodal extension in oral tongue carcinoma. Oral Oncology. 177:107960.

3.Ghag S, Jha AK, Konuparamban A, Puranik A, Rangarajan V(2026). A comparative analysis of OLINDA EXM 2.0 and MIRDcalc for Lu-177 DOTATATE radionuclide therapy, Radiation Physics and Chemistry. 245:113867.

Site of the Week

OncoKB™ is a precision oncology knowledge base developed at Memorial Sloan Kettering Cancer Center that contains biological and clinical information about genomic alterations in cancer.

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Interesting Reads

llen NC, Ringler C, Woo SH, Phipps S, Lee JY, Reyes N, Biswas R, Neyton L, Willmore A, Caryotakis S, Roginsky J, Guo L, Magnen M, Ruivo P, Langelier C; COMET Consortium; Looney M, Ma A, Auyeung V, Calfee C, Molofsky AB, Peng T (2026). NF-κB-activated fibroblasts orchestrate inflammaging and emergence of pro-inflammatory granzyme K+ T cells. Immunity.

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Early-Onset Breast Cancer: Insights From a Unique Patient Population
Upcoming Events
45th Annual Meeting of the Indian Association for Cancer Research (IACR) and International Conference On Advancements in Cancer Research: Discoveries, Therapeutics and Challenges

April 10-13, 2026

At Convocation Complex, University of Kashmir

Masterclass of Pancreatic Surgery

April 11, 2026

At ACTREC, Tata Memorial Centre, Kharghar, Navi Mumbai

CANREHAB2026:The 4th Onco-Rehabilitation Multidisciplinary Conference

April 17-19, 2026

At Tata Memorial Hospital, Parel

Do You Know?

In 2015, the FDA approved talimogene laherparepvec (T-VEC) for the treatment of some patients with metastatic melanoma that cannot be surgically removed.

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Cancer News
Lipid nanoparticles help CAR T cells melt pancreatic cancer barriers.

News-Medical.Net, 31/03/2026

The team used LNPs to equip T cells to target fibroblast activation protein, or FAP, because it is present at high levels on a subset of cancer‑associated fibroblasts -cells known to be critical for PDAC progression...

Heat-activated skin patch can kill melanoma cells without surgery.

MedicalXpress, 01/04/2026

To test the concept, the researchers placed the patch over melanoma cells cultured in the laboratory. They warmed the patch to 108 degrees Fahrenheit (42 degrees Celsius) with a low-power laser. In its now-activated state, the patch released copper ions into the melanoma cells directly beneath it...

Targeted therapy improves long-term outcomes for patients with rare mutations driving lung cancer.

Eurekalert, 01/04/2026

Patients with the RET fusion gene partners CCDC6 and KIF5B had high overall response rates to treatment. The median duration of response was longer in patients bearing CCDC6-RET (47.9 months) when compared to those with KIF5B-RET (13.1 months)...

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