Selected peer-reviewed publications

Book Chapters/Review Papers:

  • Ray, P., Bauer, E., Iyer, M., Barrio, J. R., Satyamurthy, N., Phelps, M. E., Herschman, H., and Gambhir, S. S. (2001) Monitoring Gene Therapy with Reporter Gene Imaging. Seminars in Nuclear Medicine, 31: 312-320
  • R. Paulmurugan, P. Ray, A. De, CT Chan, SS Gambhir (2005) Imaging protein–protein   interactions in living subjects. Methods, Cold Spring Harbor Laboratory, 35 695-714
  • R. Paulmurugan, P. Ray, A. De, CT Chan, SS Gambhir (2005) Imaging protein–protein   interactions in living subjects. Trends in Analytical Chemistry 24(5) 446-458
  • Ray Pritha and Sanjiv Sam Gambhir (2007) Non invasive imaging of molecular events with bioluminescent reporter genes in living subjects. Methods in Molecular Biology, The Humana Press Inc. 411:131-44
  • TF. Massoud, R. Paulmurugan, P. Ray, A. De, SS Gambhir (2007) Reporter gene imaging of protein-protein interactions in living subjects. Current Opinion in Biotechnology, ISSN: 0958-1669, Vol: 18, Issue: 1,Date: 2007-2,Pages: 31-37
  • Ray Pritha (2009) Illustrating Molecular Events with Light: A Perspective on Optical Reporter Genes. Optical Imaging of Cancer: Enhancing Detection and Resection. Springer Science and Business Media Springer Science and Business Media (London), ISBN: 978-0-387-93873-8, Pages: 139-160
  • Ray Pritha and Sanjiv Sam Gambhir (2010) Multimodality Imaging of reporter Genes. Molecular Imaging with reporter Genes. Cambridge University Press, NY, (USA), ISBN-978-0-521-88233-0, Pages: 113-126
  • Lutz A, Willmann JK, Ray P, Drescher C and Gambhir SS (2011) Early Diagnosis of Ovarian Carcinoma: Is a solution in sight? Radiology May; 259(2):329-45
  • Ray P (2011) Multimodality molecular imaging of disease progression in living subjects J Biosci. Aug;36(3):499-504
  • Ray P (2011) The pivotal role of multimodality reporter sensors in drug discovery: from cell based assays to real time molecular imaging Curr Pharm Biotechnol. Apr;12(4):539-46
  • Ray P and De A (2012) Reporter gene imaging in therapy and diagnosis.Theranostics. 2012;2(4):333-4.
  • Gaikwad SM and Ray P (2012) Non-invasive imaging of PI3K/Akt/mTOR signaling in cancer. Am J Nucl Med Mol Imaging 2012 2(4):418-431.
  • Ram K Singh, Snehal M Gaikwad, Subhoshree Chatterjee and Pritha Ray (2014) Stem Cells: The Holy Grail of Regenerative Medicine. Engineering in Translational Medicine (Ed. Weibo Cai), Springer-Volger-2014, Doi: 10-1007/978-1-4471-4372-7_2
  • Chaudhury S, Maheshwari A, Ray P. (2014) Ovarian cancer: An ever challenging malady. Biomed Res J. 1(1): 34-55
  • Smrita Chaudhury, Bhushan Thakur, Subhoshree Chatterjee and Pritha Ray (2014) Molecular Imaging Aided Improvement in Drug Discovery and Development. Current Biotechnology, 2014, 3, 218-237
  • Thakur B, Chatterjee S, Chaudhury S, Ray P (2014) Molecular imaging of therapeutic potential of Reporter probes. Curr Drug Targets. 2014 Dec 24.
  • Ray, P., De, A., Yaghoubi, S. and Khanna, A., 2015. Application of Adult Stem Cells in Medicine. Stem Cells International, 2015.

Research Articles (Till 2016):

  • S.C. Lakhotia and Pritha Ray. (1995) hsp83 mutation is a dominant enhancer of lethality associated with absence of non-protein coding hsr-? locus of D. melanogaster. Journal of Biosciences 21(2) 207-209
  • Pritha Ray and S.C. Lakhotia.(1998) Interaction of the non-protein coding developmental and stress-inducible hsr-w gene with Ras genes of Drosophila melanogaster. J. biosciences 23(4) 377-386
  • Pritha Ray, S. Gangadharan, M. Chattopadhaya, A. Bashamboo, S. Vatnagar, P. Malik and S. Ali. (1999) A bubaline derived satellite DNA probe uncovers generic affinities of gaur with other bovids. J. Biosciences 24(3) 101-105
  • S.C. Lakhotia, Pritha Ray, T.K. Rajendra and K.V. Prasanth. (1999) The non-coding transcripts of hsr-omega gene in Drosophila: do they regulate trafficking and availability of nuclear-processing factors? Current Scinece 77(4) 553-563
  • Ray, H. Pimenta, R. Paulmurugan, F. Berger, M. E. Phelps, M. Iyer, and S. S. Gambhir. (2002) Noninvasive quantitative imaging of protein-protein interactions in living subjects. PNAS 99: 3105-31102
  • Radha, Ch. Sudhakar, P. Ray and G. Swarup. (2002) Induction of cytochrome c release and apoptosis by Hck-SH3 domain-mediated signaling requires caspase-3. Apoptosis 7: 195–207
  • Pritha Ray, Anna M. Wu and Sanjiv S. Gambhir. (2003) Optical Bioluminescence and Positron Emission Tomography (PET) Imaging of a Novel Fusion Reporter Gene in Tumor Xenografts of Living Mice. Cancer Research 63: 1160-1165
  • Pritha Ray, Abhijit De, John J. Min, Roger Y. Tsien and Sanjiv S. Gambhir. (2004) Imaging Tri-fusion Multimodality Reporter Gene Expression in Living Subjects. Cancer Research 64: 1323-1330
  • Young J. Kim, Purnima Dubey, Pritha Ray, Sanjiv S. Gambhir, Owen N. Witte. (2004) Multimodality Imaging of Lymphocytic Migration Using Lentiviral-based Transduction of a Tri-Fusion Reporter Gene. Molecular Imaging and Biology 6(5) 331-340
  • Shu CJ, Guo S, Kim YJ, Shelly SM, Nijegal A, Ray P, Gambhir SS, Radu CC, Witte OW (2005) Visualization of a primary anti-tumor immune response by positron emission tomography. PNAS 102 (17) 412-17417
  • Feng Cao, Shuan Lin, Xiaoyan Xie, Pritha Ray, Manishkumar Patel, Xianzhong Zhang, Micha Drukker, Scott J. Dylla, Andrew J. Connolly, Xiaoyuan Chen, Irving L. Weissman, Sanjiv S. Gambhir, Joseph C. Wu (2006) In Vivo Visualization of Embryonic Stem Cell Survival, Proliferation, Migration, and Ablation after Cardiac Delivery. Circulation 113(7) 1005-14
  • Padmanabhan P, Otero J, Ray P, Paulmurugan R, Hoffman AR, Gambhir SS, Biswal S, Ulaner GA (2006) Visualization of telomerase reverse transcriptase (hTERT) promoter activity using a trimodality fusion reporter construct. J Nucl Med. 47(2):270-7.
  • Ray Pritha, Roger Tsien and Sanjiv Sam Gambhir (2007) Construction and validation of improved triple fusion reporter gene vectors. Cancer Research 67(7):3085-3093
  • Christophe M. Deroose, Abhijit De, Andreas M. Loening, Patrick L. Chow, Pritha Ray, Arion F. Chatziioannou, and Sanjiv S. Gambhir (2006) Multimodality Imaging of Tumor Xenografts and Metastasis in Mice with Combined Micro Positron Emission Tomography, Small Animal Computed Tomography and Bioluminescence Imaging. J Nucl Med 48(2):295-303
  • Shariar S Yaghoubi, Remi J Cresout, Pritha Ray, C Garrison Fathman and Sanjiv S Gambhir (2007) Multimodality Imaging of T Cell Hybridoma Trafficking in Collagen Induced Arthritic Mice: Image Based Estimation of the Number of Cells Accumulating in the Mouse Paws. Journal of biomedical Optics 12(6):064025
  • A.M. Lutz, P. Ray, J.K. Willmann, Charles Drescher and Sanjiv Sam Gambhir (2007) FDG-Accumulation in Ovarian Carcinoma Cell Lines. Molecular Imaging and Biology 9(5):260-6
  • Chin FT, Namavari M, Levi Z, Subbarayan M, Ray P, Chen X and Gambhir SS (2008) Semiautomated Radiosynthesis and Biological Evaluation of [(18)F]FEAU: A Novel PET Imaging Agent for HSV1-tk/sr39tk Reporter Gene Expression.Mol Imaging Biol. Mar-Apr;10(2):82-91
  • Cecic I, Chan DA, Sutphin PD, Ray P, Gambhir SS, Giaccia Aj, Graves EE (2007) Oxygen sensitivity of reporter genes: implications for preclinical imaging of tumor hypoxia. Mol Imaging. 2007 Jul-Aug;6(4):219-28
  • Lutz AM, Willmann JK, Cochran FV, Ray P, Gambhir SS (2008) Cancer screening: A mathematical model relating secreted blood biomarker levels to tumor sizes. PLoS Med. Aug 19;5(8):e170.
  • Ray P, De A, Patel MK, Gambhir SS (2008) A Monitoring caspase-3 activation with a multimodality imaging sensor in living subjects. Clinical Cancer Research 15;14(18):5801-9
  • Ray P, Yaghoubi SS (2008) CD147: A potential regulator of oncogenesis: Non invasive imaging of CD147 in living subjects. Cancer Biol Ther. 2008 Jul;7(7):1071-2
  • Lee SW, Padmanabhan P, Ray P, Gambhir SS, Doyle T, Contag C, Goodman SB, Biswal (2009) Stem-cell mediated accelerated bone healing observed with in vivo molecular and small animal imaging technologies in a model of skeletal injury. J Orthop Res. Mar;27(3):295-302
  • De A, Ray P, Loening AM, Gambhir SS (2009) BRET3: a red-shifted bioluminescence resonance energy transfer (BRET)-based integrated platform for imaging protein-protein interactions from single live cells and living animals. FASEB J. Aug;23(8):2702-9.
  • Srivastava M, Nambiar M, Sharma S, Karki SS, Goldsmith G, Hegde M, Kumar S, Pandey M, Singh RK, Ray P, Natarajan R, Kelkar M, De A, Choudhury B and Raghavan SC (2012) An inhibitor of Nonhomolgous End-Joining abrogates double-strand break repair and impedes cancer progression. Cell 151; 1-14
  • Gaikwad SM, Gunjal L, Junutula AR, Astanehe A, Gambhir SS and Ray P (2013) Non-invasive imaging of Phosphoinositide-3-kinase-catalytic-subunit-alpha (PIK3CA) promoter modulation in small animal models. PLos One 8(2):e55971. doi: 10.1371/journal.pone.0055971
  • Yan X, Ray P, Paulmurugan R, Tong R, Gong Y, Sathirachinda A, Wu JC and Gambhir SS (2013) A transgenic tri- modality reporter mouse. PLoS One 8(8) e73580.Doi:10.13.1371/journal.pone.0073580
  • P Sachar S, Chandra S, Bahadur D, Ray P, Khanna A (2014) Cellular internalization and detailed toxicity analysis of protein-immobilized iron oxide nanoparticles. J Biomed Mater Res B Appl Biomater. Apr 30. doi: 10.1002/jbm.b.33178
  • Singh RK, Gaikwad SM, Jinager A, Chaudhury S, Maheshwari A, Ray P (2014) IGF-1R inhibition potentiates cytotoxic effects of chemotherapeutic agents in early stages of chemoresistant ovarian cancer cells. Cancer Letter. Nov 28;354(2):254-62
  • Nagraj J, Chatterjee S, Pal T, Sakpal AS, Gota V, Ramaa CS, Ray P (2014) A novel series of di-fluorinated propanedione derivatives synergistically augment paclitaxel mediated caspase 3 activation in ovarian cancer cells. J Cancer Res Ther. Jul-Sep;10(3):701-9.
  • Gaikwad SM, Thakur B, Sakpal A, Singh RK and Ray P (2015) Differential activation of NF-κB signaling is associated with platinum and taxane resistance in MyD88 deficient epithelial ovarian cancer cells. Int J Biochem Cell Biol. 2015 Apr;61:90-102. doi: 10.1016/j.biocel.2015.02.001. Epub 2015 Feb 11
  • Shetake, N.G., Kumar, A., Gaikwad, S., Ray, P., Desai, S., Ningthoujam, R.S., Vatsa, R.K. and Pandey, B.N., 2015. Magnetic nanoparticle-mediated hyperthermia therapy induces tumour growth inhibition by apoptosis and Hsp90/AKT modulation. International Journal of Hyperthermia, pp.1-11.
  • Singh, M., Singh, S.K., Thakur, B. and Ray, P., 2015. Design and Synthesis of Novel Schiff base-benzothiazole hybrids as potential Epidermal Growth Factor Receptor (EGFR) Inhibitors. Anti-Cancer Agents in Medicinal Chemistry.
  • Jadhav V, Ray P, Sachdeva G, Bhatt P. Biocompatible arsenic trioxide nanoparticles induce cell cycle arrest by p21WAF1/CIP1 expression via epigenetic remodeling in LNCaP and PC3 cell lines. Life Sci. 148: 41-52, 2016.
  • Lina Pradhan ‡, Bhushan Thakur ‡, Rohit Srivastava, Pritha Ray*, Dhirendra Bahadur*, ‘Assessing therapeutic potential of magnetic mesoporous nanoassemblies for chemo-resistant tumors.’ Theranostics 2016. (‡ both the authors contributed equally, * Corresponding authors)(Accepted)