VDAC2

                                                                              (Voltage-dependent anion channel 2)

  • Alias                                 (According to NCBI)

 
  • voltage-dependent anion channel 2
  • Voltage-dependent anion-selective channel protein 2 (VDAC-2) (hVDAC2) (Outer mitochondrial
    membrane protein porin 2).
  • Forms a channel through the mitochondrial outer membrane that allows diffusion of small hydrophilic molecules. The channel adopts an open conformation at low or zero membrane potential and a closed conformation at potentials above 30-40 mV. The open state has a weak anion selectivity whereas the closed state is cation- selective.
  • Location: 10q22
  • Orientation: Plus strand
  • Size: 59,484 bases
  • 10 Exons
  • DNA Sequence: NT_008583

  • CGH (10q22): Losses (%) -10.0   Gain (%)  0.0   Amplifications  0.0
  • Mutations and SNPs  (According to HGMD and SNP)

 
  • m-RNA                           (According to NCBI and CGAP)

 

  
  • Size: 347 amino acids; 38092 Da
  • Sub cellular location: Outer mitochondrial membrane.
  • Protein domains:
                               
  • Pathways and interactions (According to BioCarta, DIP)
  • Pathways:
  • Interactions:
  • Clinical                            (According to OMIM, PubMed)