TSPAN2

(Tetraspanin 2)

 

  • Alias                                 (According to NCBI)

 
  • FLJ12082 
  • TSPAN2
  • tetraspan 2 
  • tetraspan TM4SF 
  • tetraspanin 2
  • Tetraspanin 2 (Tspan-2).
  • The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility.
  • Location: 1p13.1
  • Orientation: minus strand
  • Size: 41451 bp 
  • 8 exons
  • DNA sequence (Human): NC_000001. 

  • CGH (1p13.1): Losses (%) -6.3   Gain (%)  2.5   Amplifications  0.0
  • Mutations and SNPs  (According to HGMD and SNP)

 
  • m-RNA                           (According to NCBI and CGAP)

 
  • Size: 221 amino acids; 24147 Da
  • Catalytic activity:

  • Subcellular location: Integral membrane protein

  • Protein domains

        

  • Pathways and interactions (According to BioCarta, DIP)

  • Pathway:

  • Protein interactions:
  • Clinical                            (According to OMIM, PubMed)