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Alias (According to NCBI)
- Tenascin R (restrictin, janusin)
- Tenascin-R (Restrictin)
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Description
(According to SwissProt)
- Tenascin-R (TNR) is an extracellular matix protein expressed primarily in the central nervous system. It is a member of the tenascin (TN) gene family, which includes at least 3 genes in mammals: TNC (or hexabrachion; MIM 187380), TNX (TNXB; MIM 600985), and TNR (Erickson, 1993). The genes are expressed in distinct tissues at different times during embryonic development and are present in adult tissues.[supplied by OMIM]
- Chromosomal location
(According to NCBI, CGH: progenetix)
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CGH (1q24): Losses (%) -2.5 Gain (%) 11.3 Amplifications 0.0
- HGMD:
- SNPs: TNR
- Size:1358 amino acids; 149547 Da
- Catalytic activity:
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Subcellular location: Secreted; extracellular matrix
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Protein domains
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Pathway:
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Protein interactions:
- Tissue expression: PubMed Reference
- Human Protein Atlas (HPA) :
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OMIM: 601995
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PubMed: Early detection Diagnosis Prognosis Therapy