PLAG1

                                                                                            (pleomorphic adenoma gene-1)

  • Alias                                 (According to NCBI)

 
  • LOT1 
  • ZAC 
  • ZAC1
  • Human LOT1 mRNA, complete cds
  • PLAG-like 1
  • ZAC tumor supressor 
  • pleiomorphic adenoma gene-like 1
  • pleomorphic adenoma gene-like 1
  • Zinc finger protein PLAGL1 (Pleiomorphic adenoma-like protein 1)
  • This gene encodes a C2H2 zinc finger protein with transactivation and DNA-binding activity. This gene has been shown to exhibit antiproliferative activities and is a tumor suppressor gene candidate.
  • Location: 8q12
  • Orientation: Minus strand
  • Size: 68,116 bases
  • 6 Exons
  • DNA Sequence: NT_025741

  • CGH (8q12):  Losses (%) - 1.3   Gain (%)  21.3   Amplifications  0.0
  • Mutations and SNPs (According to HGMD and SNP)
  • HGMD :
  • m-RNA                       (According to NCBI and CGAP)

 
  • Size: 411 amino acids; 44652 Da
  • Sub cellular location: Nuclear
  • Protein domains:

                                                   

  • Pathways and interactions (According to BioCarta, DIP)
  • Pathways:
  • Interactions:
  • Clinical                            (According to OMIM, PubMed)