KRT9

(Keratin 9)

Alias (According to NCBI)	EPPK K9 keratin 9 (epidermolytic palmoplantar keratoderma) Keratin, type I cytoskeletal 9 (Cytokeratin 9) (K9) (CK 9).
Description (According to SwissProt)	This gene encodes the type I keratin 9, an intermediate filament chain expressed only in the terminally differentiated epidermis of palms and soles. Mutations in this gene cause epidermolytic palmoplantar keratoderma.
Chromosomal location (According to NCBI, CGH: progenetix)	Location: 17q21.1-q21.2 Orientation: minus strand Size: 6215 bp 8 exons DNA sequence (Human): NC_000017. CGH (12q12-13): Losses (%) -3.8 Gain (%) 1.3 Amplifications (%) 0.2
Mutations and SNPs (According to HGMD and SNP)	HGMD : KRT9 SNPs: KRT9
m-RNA (According to NCBI and CGAP)	mRNA sequence (Human):NM_000226 Size:2287 bp cDNA libraries:
Protein (According to SwissProt, Swiss2D, PDB, dbPTM)	Size: 622 amino acids; 61987 Da Catalytic activity: Subcellular location: intracellular,cytoplasm,cytoskeleton,intermed filament Protein domains Protein sequence (Human): P35527 Homologous genes: KRT9 2D PAGE : P35527 3D Structure: PTM: KRT9
Pathways and interactions (According to BioCarta, DIP)	Pathway: Keratinocyte Differentiation Protein interactions:
Tissue (According to GeneNote, PubMed, HPA)	Tissue expression: PubMed Reference Human Protein Atlas (HPA):
Clinical (According to OMIM, PubMed)	OMIM: 607606 PubMed: Early detection Diagnosis Prognosis Therapy