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ICAM1

(Intercellular adhesion molecule 1)

Alias (According to NCBI)	BB2 CD54 cell surface glycoprotein P3.58 intercellular adhesion molecule 1 (CD54), human rhinovirus receptor Intercellular adhesion molecule-1 precursor (ICAM-1) (Major group rhinovirus receptor) (CD54 antigen)
Description (According to SwissProt)	ICAM1 (CD54) is typically expressed on endothelial cells and cells of the immune system. ICAM1 binds to integrins of type CD11a / CD18, or CD11b / CD18. ICAM1 is also exploited by Rhinovirus as a receptor.
Chromosomal location (According to NCBI, CGH: progenetix)	Location: 19p13.3-p13.2 Orientation: Plus strand Size: 15,527 bases 7 Exons DNA Sequence: NT_011295 CGH (19p13.3-13.3): Losses (%) -11.3 Gain (%) 8.8 Amplifications (%) 0.0
Mutations and SNPs (According to HGMD and SNP)	HGMD: ICAM1 SNPs: ICAM1
m-RNA (According to NCBI and CGAP)	m-RNA Sequence: NM_000201 Size: 2986 bp c-DNA Libraries: ICAM1
Protein (According to SwissProt, Swiss2D, PDB, dbPTM)	Size:532 amino acids; 57826 Da Sub cellular location: Type I membrane protein Protein domains: Protein sequence: P05362 Homologous genes: ICAM1 3D Structure: 1IAM PTM: ICAM1
Pathways and interactions (According to BioCarta, DIP)	Pathways: Adhesion Molecules on Lymphocyte B Lymphocyte Cell Surface Molecules Cells and Molecules involved in local acute inflammatory response CTL mediated immune response against target cells Monocyte and its Surface Molecules Neutrophil and Its Surface Molecules T Cytotoxic Cell Surface Molecules T Helper Cell Surface Molecules Interactions: 629N
Tissue (According to GeneNote, PubMed, HPA)	Tissue expression: PubMed Reference Human Protein Atlas (HPA): HPA002126
Clinical (According to OMIM, PubMed)	OMIM:147840 PubMed: Early detection Diagnosis Prognosis Therapy