ACTB

(Actin beta)

 

  • Alias                                 (According to NCBI)

 
  • actin, beta
  • beta cytoskeletal actin
  • Actin, cytoplasmic 1 (Beta-actin)
  • Beta actin is one of six different actin isoforms which have been identified. ACTB is one of the two nonmuscle cytoskeletal actins. Actins are highly conserved proteins that are involved in cell motility, structure and integrity. Alpha actins are a major constituent of the contractile apparatus
  • Location:7p15-p12
  • Orientation:  minus strand
  • Size: 3436 bp
  • 6 exons
  • DNA sequence (Human):NC_000007 

  • CGH (7p15-p12):  Losses - 0.0     Gain 12.5     Amplifications  0.0

  • Mutations and SNPs (According to HGMD and SNP)

 
  • HGMD (Human Gene Mutation Database):
  • SNP: ACTB
  • m-RNA                       (According to NCBI and CGAP)

 

  • mRNA sequence (Human):NM_001101

  • Size:1793 bp 

  • cDNA libraries: ACTB

  • Size: 375 amino acids; 41736 Da
  • Catalytic activity:

  • Subcellular location: Cytoplasmic.

  • Protein domains

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  • Protein sequence (Human): P60709

  • Homologous genes: ACTB

  • 2D PAGE:P60709

  • 3D Structure:

  • Pathways and interactions (According to BioCarta, DIP)

  • Clinical                            (According to OMIM, PubMed)