SFN

                                                                                   ( stratifin/14-3-3 protein sigma )

  • Alias                                 (According to NCBI)

 
  • HME1
  • stratifin
  • 14-3-3 protein sigma (Stratifin) (Epithelial cell marker protein 1).
  • Oligoribonuclease, mitochondrial precursor (EC 3.1.-.-) (Small fragment nuclease) (CGI-114).
  • It is P53-regulated inhibitor of G2/M progression. Present mainly in tissues enriched in stratified squamous keratinising epithelium.
  • Location:1p35.3
  • Orientation: Plus strand
  • Size: 1,327 bases
  • 1 Exon
  • DNA Sequence: NT_037485

               

  • CGH (1p35.3): Losses (%) -5.0   Gain (%)  1.3   Amplifications  0.0
  • Mutations and SNPs  (According to HGMD and SNP)

 
  • HGMD:
  • SNP: SFN
  • m-RNA                           (According to NCBI and CGAP)

 

  
  • Protein                                  (According to SwissProt, Swiss2D, PDB)
  • Size:248 amino acids; 27774 Da
  • Sub cellular location: Cytoplasmic or may be secreted by a non- classical secretory pathway
  • Protein domains:

                                                   
  • Pathways and interactions (According to BioCarta, DIP)
  • Pathways:
  • Interactions:
  • Clinical                            (According to OMIM, PubMed)