Histone KINASE
Kinases are enzymes that transfer phosphate groups from high-energy donor molecules, such as ATP, to specific target molecules (substrates), the process termed as phosphorylation. Phosphorylation of a protein causes it to be bound to other proteins which have "recognition domains". As a result of binding a particular protein, a distinct signaling system may be activated or inhibited.
| Reference |
Chromosome |
Location |
Site of Modification |
| Chromosome: 11 | 11q22-q23 | H2A.XS139 | |
| AURKA | Chromosome: 20 | 20q13.2-q13.3 | H3CENPAS6 |
| AURKB | Chromosome: 17 | 17p13.1 | H3S10,H3S28,H3 CENPAS6 |
| GSG2 | Chromosome: 17 | 17p13 | H3T3 |
| MLTK | Chromosome: 2 | 2q24.2 | H3S28 |
| RPS6KA5 | Chromosome: 14 | 14q31-q32.1 | H2AS1,H3S28 |
| STK4 | Chromosome: 20 | 20q11.2-q13.2 | H2BS14 |
| ZIPK | Chromosome: 19 | 19p13.3 | H3T11 |