This mark is mostly enriched in promoter region and associated with gene activation.

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H3K4me3 infosheet
Modified variants Histone H3.3, Histone H3.3C
Modified Isoforms Histone H3.1, Histone H3.2
Writer/s Lysine Methyltransferase 2A, Lysine Methyltransferase 2B, Lysine Methyltransferase 2C, PR/SET Domain 9, SET And MYND Domain Containing 3, SET Domain Containing 1A, SET Domain Containing 1B
Eraser/s Lysine Demethylase 2B, Lysine Demethylase 5A, Lysine Demethylase 5B, Lysine Demethylase 5C, PHD Finger Protein 8, Ribosomal Oxygenase 1
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Sites of Lysine Methylation H3K14me2, H3K27me2, H3K27me3, H3K36me2, H3K36me3, H3K4me1, H3K4me2, H3K4me3, H3K79me2, H3K79me3, H3K9me1, H3K9me2, H3K9me3, H4K20me1, H4K20me2, H4K20me3, TH2BK110me, TH2BK117me, TH2BK36me, TH2BK7me