Histone Arginine Methylation

Histone arginine methylation is strongly associated with gene activation. Arginine methylation adds ~14 Da to the overall size of the histone protein but does not perturb the charge on the residue.

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Sites of histone Arginine Methylation
Site of modification Writers Erasers
H3R8me2 Protein Arginine N-methyltransferase 5-
H3R17me2 Histone-arginine Methyltransferase CARM1-
H4R3me2 Protein Arginine N-methyltransferase 5 Arginine Demethylase And Lysine Hydroxylase