Histone H2A

Histone H2A is a 14 kDa protein. There are nine H2A isoforms which are coded by twelve genes. The genes are in two clusters on chromosome number 2 and 17. H2A undergoes different post-translational modifications like acetylation, methylation, citrullination, phosphorylation etc.


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Isoform of histone H2A
Isoform (UniprotKB recommended name) UniprotKB Accession No. of coding gene(s)
Histone H2A type 1-C or Hist1h2acG3V9C03 (HIST1H2AC, HIST1H2AI, HIST1H2AN)
Histone H2A type 1-F or Hist1h2afQ6I8Q61 (HIST1H2AF)
Histone H2A type 1-H or H2A.1K7R8M01 (HIST1H2AH)
Histone H2A type 1-K or Hist1h2akD3ZVK71 (HIST1H2AK)
Histone H2A type 2-A or H2A.2K7S2S21 (HIST2H2AA2)
Histone H2A type 2-B or Hist2h2abD3ZWE01 (HIST2H2AB)
Histone H2A type 2-C or Hist2h2acD4ACV31 (HIST2H2AC)
Histone H2A type 3 or Hist3h2aQ4FZT61 (HIST3H2A)
Histone H2A type 1-A or Th2aQ007281 (HIST1H2AA/H2AC1)