Sirtuin-1

This NAD dependent histone deacetylase removes mark from H3K9 and H4K16 leads to transcription repression.

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Sirtuin-1 infosheet
UniprotKB AccessionA0A0G2JZ79
Alternative Name(s)-
Eraser for PTM/s H3K9ac, H4K16ac
EC number 3.5.1.98
No. of coding genesSirtuin-1 is coded by following 1 non-allelic gene/s
Gene symbolSIRT1
Promoter region (-700 TSS +300)Get sequence
Aliases-
GeneID309757
RGD1308542
RefSeq mRNAXM_008772947.2, XM_017601789.1, XM_017601788.1, XM_008774950.2
RefSeq ProteinXP_017457278.1, XP_017457277.1, XP_008771169.1
PubmedFor more information

Lysine deacetylase Histone Deacetylase 1, Histone Deacetylase 10, Histone Deacetylase 11, Histone Deacetylase 2, Histone Deacetylase 3, Histone Deacetylase 4, Histone Deacetylase 5, Histone Deacetylase 6, Histone Deacetylase 7, Histone Deacetylase 8, Histone Deacetylase 9, Sirtuin 2, Sirtuin 3, Sirtuin 6, Sirtuin-1