This is catalyzed by SUV420H2 and it represents a specific tag for epigenetic transcriptional repression.

Download table as Excel
H4K20me3 infosheet
Modified variants-
Modified IsoformsHistone H4
Writer/s Histone-lysine Methyltransferase 5B, Histone-lysine N-methyltransferase 5C
PubmedFor more Information

Sites of Lysine Methylation H1K106me, H1K26me, H1K34me, H1k46me, H1K63me, H3K122me, H3K27me, H3K27me2, H3K27me3, H3K36me1, H3K36me2, H3K36me3, H3K4me1, H3K4me2, H3K4me3, H3K79me1, H3K79me2, H3K79me3, H3K9me1, H3K9me2, H3K9me3, H4K20me1, H4K20me2, H4K20me3