It is repressive modification and is catalyzed by EZH1.

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H3K27me2 infosheet
Modified variantsHistone H3.3, Histone H3.3C, Histone H3-like centromeric protein A
Modified IsoformsHistone H3.1, Histone H3.2
Writer/s Histone-lysine N-methyltransferase EZH1, Histone-lysine N-methyltransferase EZH2
Eraser/s Lysine-specific Demethylase 6B
PubmedFor more Information

Sites of Lysine Methylation H1K106me, H1K26me, H1K34me, H1k46me, H1K63me, H3K122me, H3K27me, H3K27me2, H3K27me3, H3K36me1, H3K36me2, H3K36me3, H3K4me1, H3K4me2, H3K4me3, H3K79me1, H3K79me2, H3K79me3, H3K9me1, H3K9me2, H3K9me3, H4K20me1, H4K20me2, H4K20me3