H2AK119ub

H2AK119 ubiquitination is mediated by RING1 and it is known for polycomb mediated gene silencing.


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H2AK119ub infosheet
Modified variantsHistone H2A.J, Histone H2A.x
Modified IsoformsHistone H2A type 1, Histone H2A type 1-F, Histone H2A type 1-H, Histone H2A type 1-K, Histone H2A type 1-P, Histone H2A type 2-C, Histone H2A type 1-F, Histone H2A type 1-H, Histone H2A type 1-K, Histone H2A type 2-A, Histone H2A type 2-B, Histone H2A type 3
Writer/s E3 Ubiquitin-protein Ligase RING1, E3 Ubiquitin-protein Ligase RING2
Eraser/s-
PubmedFor more Information

Sites of Lysine Ubiquitination H2AK119ub, H2AK121ub, H2BK120ub, H2BK121ub, H4K91ub1