Histone Lysine Acetyltransferase

The acetylation of histones is mediated by Lysine acetyltransferases (KATs). There are total seven proteins to demonstrate the histone acetyltransferases activity in the mouse.

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Different Histone Lysine Acetyltransferase
Enzyme (UniprotKB recommended name) Coding gene/s Site of histone modification
Histone Acetyltransferase KAT2AKAT2AH4K5ac, H4K8ac, H4K12ac, H4K16ac, H2BK12ac, H3K9ac, H3K14ac, H3K18ac, H3K24ac, H3K23ac, H2AK4ac, H2AK7ac, H2AK11ac, H2AK36ac, H3K56ac
Histone Acetyltransferase KAT2BKAT2BH4K5ac, H4K8ac, H4K12ac, H4K16ac, H3K9ac, H3K14ac, H3K18ac, H3K24ac, H3K23ac, H3K56ac
Histone Acetyltransferase KAT5KAT5H2AK4ac, H2AK7ac, H2AK11ac, H2AK36ac, H4K5ac, H4K8ac, H4K12ac, H4K16ac
Histone Acetyltransferase KAT6AKAT6AH4K5ac, H4K8ac, H4K12ac, H4K16ac, H3K9ac, H3K14ac, H3K18ac, H3K24ac, H3K23ac, H3K56ac
Histone Acetyltransferase KAT6BKAT6B
Histone Acetyltransferase KAT7KAT7H4K5ac, H4K8ac, H4K12ac, H4K16ac
Histone Acetyltransferase KAT8KAT8H4K16ac