Sites of histone lysine ubiquitination
Site of modification Writers Erasers
H2AK119ub E3 ubiquitin-protein ligase RING2, E3 ubiquitin-protein ligase RING1 Histone H2A deubiquitinase MYSM1
H2AK121ub E3 ubiquitin-protein ligase RING2-
H2BK120ub E3 ubiquitin-protein ligase BRE1A, E3 ubiquitin-protein ligase RBX1, E3 ubiquitin-protein ligase BRE1B-
H4K91ub E3 ubiquitin-protein ligase DTX3L-