Activating modification, reported to be enriched at the transcription start site (TSS) and along gene bodies.

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H4K16ac infosheet
Modified variants-
Modified Isoforms Histone H4
Writer/s CREB-binding protein, Histone acetyltransferase KAT2A, Histone acetyltransferase p300, Probable histone acetyltransferase MYST1
Eraser/s NAD-dependent deacetylase sirtuin-1 NAD-dependent deacetylase sirtuin-2
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Sites of lysine acetylation H1K25ac, H2AK5ac, H2AK9ac, H2BK120ac, H2BK12ac, H2BK15ac, H2BK16ac, H2BK20ac, H2BK46ac, H2BK5ac, H3K14ac, H3K18ac, H3K23ac, H3K27ac, H3K36ac, H3K4ac, H3K56ac, H3K64ac, H3K9ac, H4K12ac, H4K16ac, H4K5ac, H4K8ac, H4K91ac