Dimethylation of H3R8 is mediated by PRMT5 and is known to regulate rRNA promoter activity.

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H3R8me2 infosheet
Modified variants Histone H3.3
Modified Isoforms Histone H3.1, Histone H3.2
Writer/s Protein arginine N-methyltransferase 5
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Sites of arginine methylation H2AR3me2, H3R17me1, H3R17me2, H3R26me1, H3R2me1, H3R2me2, H3R42me2, H3R8me2, H4R3me1, H4R3me2