Histone Variants

Histone variants are non-canonical (non-allelic) variants of histones - with a difference of variations in amino acids from few to several. These are expressed at low levels throughout the cell cycle compared with their canonical equivalents and therefore known as replication-independent histones. Histone variants are found as single genes distributed all through the genome, and there transcripts have poly(A) tails. They are known to confer novel structural and functional properties along with variants specific post-translational modifications.

Types of histone variants Histone H1, Histone H2A, Histone H2B, Histone H3, Histone H4