Histone Arginine deiminases

Protein arginine deiminases (PADs) catalyze the hydrolysis of guanidinium side chains of arginine residues to form citrulline and ammonia. Five types of PADs are found in humans; namely PAD1, PAD2, PAD3, PAD4, and PAD6.

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Different histone Arginine deiminases
Enzyme (UniprotKB recommended name) Coding gene/s Site of histone modification
Protein-arginine deiminase type-4PADI4H3R2ci, H3R8ci, H3R17ci, H3R26ci, H2AR3ci, H4R3ci

Epidrugs for deiminasesPADi