Serine/threonine-protein kinase 12

Aurora B is Ser/Thr protein kinase which mediates the H3 Serine 10 phosphorylation during mitosis.

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Serine/threonine-protein kinase 12 infosheet
UniprotKB AccessionQ96GD4
Alternative Name(s)Aurora kinase B, Aurora- and IPL1-like midbody-associated protein 1 (AIM-1), Aurora/IPL1-related kinase 2 (ARK-2, Aurora-related kinase 2), STK-1, Serine/threonine-protein kinase aurora-B
Writer for PTM/s H3S10ph, H3S6ph, H3S28ph
EC number 2.7.11.1
No. of coding genesSerine/threonine-protein kinase 12 is coded by following 1 non-allelic gene/s
Gene nameaurora kinase B
Gene symbolAURKB
Promoter region (-700 TSS +300)Get sequence
Previous Symbol/sSTK12
AliasesAik2, IPL1, AurB, AIM-1, ARK2, STK5
GeneID9212
HGNC11390
RefSeq mRNANM_004217.2
RefSeq ProteinNP_004208.2
TCGA Gene Expression (Firebrowse)AURKB
mir TargetsAURKB
PubmedFor more Information

Serine/threonine/tyrosine kinases Cyclin-dependent kinase 17, Cyclin-dependent kinase 3, Cyclin-dependent kinase 5, Death-associated protein kinase 3, DNA-dependent protein kinase catalytic subunit, Glycogen synthase kinase-3 beta, Inhibitor of nuclear factor kappa-B kinase subunit alpha, LIM domain kinase 2, Microtubule-associated serine/threonine-protein kinase-like, Mitogen-activated protein kinase kinase kinase 8, Mitogen-activated protein kinase kinase kinase MLT, Mitotic checkpoint serine/threonine-protein kinase BUB1, Protein kinase C beta type, Protein kinase C delta type, Ribosomal protein S6 kinase alpha-4, Ribosomal protein S6 kinase alpha-5, Serine-protein kinase ATM, Serine/threonine-protein kinase 10, Serine/threonine-protein kinase 12, Serine/threonine-protein kinase 4, Serine/threonine-protein kinase ATR, Serine/threonine-protein kinase haspin, Serine/threonine-protein kinase N1, Serine/threonine-protein kinase Nek6, Serine/threonine-protein kinase Nek9, Serine/threonine-protein kinase PAK 2, Serine/threonine-protein kinase tousled-like 1, Tyrosine-protein kinase BAZ1B, Tyrosine-protein kinase JAK2