Probable histone-lysine N-methyltransferase NSD2

NSD2 is histone methyltransferase known for H3K27 methylation.

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Probable histone-lysine N-methyltransferase NSD2 infosheet
UniprotKB AccessionO96028
Alternative Name(s)Multiple myeloma SET domain-containing protein, Nuclear SET domain-containing protein 2, Protein trithorax-5, Wolf-Hirschhorn syndrome candidate 1 protein
Writer for PTM/s H3K36me3, H4K20me1, H4K20me3
EC number 2.1.1.43
No. of coding genesProbable histone-lysine N-methyltransferase NSD2 is coded by following 1 non-allelic gene/s
Gene nameWolf-Hirschhorn syndrome candidate 1
Gene symbolWHSC1
Promoter region (-700 TSS +300)Get sequence
Previous Symbol/s-
AliasesMMSET, NSD2
GeneID7468
HGNC12766
RefSeq mRNANM_001042424.2NM_007331.1NM_133330.2NM_133331.2NM_133334.2NM_133335.3
RefSeq ProteinNP_001035889.1NP_015627.1NP_579877.1NP_579878.1NP_579889.1NP_579890.1
TCGA Gene Expression (Firebrowse)WHSC1
mir TargetsWHSC1
PubmedFor more Information

Lysine methyltransferases Histone-lysine N-methyltransferase EZH1, Histone-lysine N-methyltransferase EZH2, Histone-lysine N-methyltransferase MLL, Histone-lysine N-methyltransferase MLL2, Histone-lysine N-methyltransferase MLL3, Histone-lysine N-methyltransferase MLL4, Histone-lysine N-methyltransferase MLL5, Histone-lysine N-methyltransferase NSD3, Histone-lysine N-methyltransferase PRDM9, Histone-lysine N-methyltransferase SETD1A, Histone-lysine N-methyltransferase SETD1B, Histone-lysine N-methyltransferase SETD2, Histone-lysine N-methyltransferase SETD7, Histone-lysine N-methyltransferase SETD8, Histone-lysine N-methyltransferase SETDB1, Histone-lysine N-methyltransferase SETDB2, Histone-lysine N-methyltransferase SETMAR, Histone-lysine N-methyltransferase SUV39H1, Histone-lysine N-methyltransferase SUV39H2, Histone-lysine N-methyltransferase SUV420H1, Histone-lysine N-methyltransferase SUV420H2, Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific, Histone-lysine N-methyltransferase, H3 lysine-79 specific, Histone-lysine N-methyltransferase, H3 lysine-9 specific 3, Histone-lysine N-methyltransferase, H3 lysine-9 specific 5, N-lysine methyltransferase SMYD2, PR domain zinc finger protein 2, Probable histone-lysine N-methyltransferase ASH1L, Probable histone-lysine N-methyltransferase NSD2, SET and MYND domain-containing protein 3