Poly [ADP-ribose] polymerase 1

PARP1 mediates the poly ADP-ribosylation of histone H1 in context of DNA damage repair.

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Poly [ADP-ribose] polymerase 1 (PARP-1) infosheet
UniprotKB AccessionP09874
Alternative Name(s)NAD(+) ADP-ribosyltransferase 1 (ADPRT 1), Poly[ADP-ribose] synthase 1
Writer for PTM/s H2AK13ar, H2BK30ar, H3K27ar, H3K37ar, H4K16ar
EC number 2.4.2.30
No. of coding genesPoly [ADP-ribose] polymerase 1 is coded by following 1 non-allelic gene/s
Gene namepoly (ADP-ribose) polymerase 1
Gene symbolPARP1
Promoter region (-700 TSS +300)Get sequence
Previous Symbol/sPPOL, ADPRT
AliasesPARP
GeneID142
HGNC270
RefSeq mRNANM_001618.3
RefSeq ProteinNP_001609.2
TCGA Gene Expression (Firebrowse)PARP1
mir TargetsPARP1
PubmedFor more Information

Lysine ribosylases Poly [ADP-ribose] polymerase 1