NAD-dependent deacetylase sirtuin-2

SIRT2 is class III of histone deacetylases known for deacetylation of H4K16 during mitosis.

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NAD-dependent deacetylase sirtuin-2 infosheet
UniprotKB AccessionQ8IXJ6
Alternative Name(s)SIR2-like protein 2
Eraser for PTM/s H4K16ac, H3K56ac
EC number 3.5.1.-
No. of coding genesNAD-dependent deacetylase sirtuin-2 is coded by following 1 non-allelic gene/s
Gene namesirtuin 2
Gene symbolSIRT2
Promoter region (-700 TSS +300)Get sequence
Previous Symbol/sSIR2L
AliasesNULL
GeneID22933
HGNC10886
RefSeq mRNANM_001193286.1NM_030593.2NM_012237.3
RefSeq ProteinNP_001180215.1NP_085096.1NP_036369.2
TCGA Gene Expression (Firebrowse)SIRT2
mir TargetsSIRT2
PubmedFor more Information

Lysine deacetylases Histone deacetylase 1, Histone deacetylase 10, Histone deacetylase 11, Histone deacetylase 2, Histone deacetylase 3, Histone deacetylase 4, Histone deacetylase 5, Histone deacetylase 6, Histone deacetylase 7, Histone deacetylase 8, Histone deacetylase 9, NAD-dependent deacetylase sirtuin-1, NAD-dependent deacetylase sirtuin-2, NAD-dependent deacetylase sirtuin-3, mitochondrial, NAD-dependent deacetylase sirtuin-6