NAD-dependent deacetylase sirtuin-1

SIRT1 is histone deacetylase which belongs to NAD+ dependent Class III of histone deacetylases.

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NAD-dependent deacetylase sirtuin-1 (hSIRT1) infosheet
UniprotKB AccessionQ96EB6
Alternative Name(s)SIR2-like protein 1 (hSIR2)
Eraser for PTM/s H4K16ac, H3K9ac, H1K25ac
EC number 3.5.1.-
No. of coding genesNAD-dependent deacetylase sirtuin-1 is coded by following 1 non-allelic gene/s
Gene namesirtuin 1
Gene symbolSIRT1
Promoter region (-700 TSS +300)Get sequence
Previous Symbol/s-
AliasesSIR2L1
GeneID23411
HGNC14929
RefSeq mRNANM_001142498.1NM_012238.4
RefSeq ProteinNP_001135970.1NP_036370.2
TCGA Gene Expression (Firebrowse)SIRT1
mir TargetsSIRT1
PubmedFor more Information

Lysine deacetylases Histone deacetylase 1, Histone deacetylase 10, Histone deacetylase 11, Histone deacetylase 2, Histone deacetylase 3, Histone deacetylase 4, Histone deacetylase 5, Histone deacetylase 6, Histone deacetylase 7, Histone deacetylase 8, Histone deacetylase 9, NAD-dependent deacetylase sirtuin-1, NAD-dependent deacetylase sirtuin-2, NAD-dependent deacetylase sirtuin-3, mitochondrial, NAD-dependent deacetylase sirtuin-6