Lysine-specific demethylase 2B
JHDM1B is histone demethylases that is involved in demethylation of trimethylated H3K4 and dimethylated H3K36.
| UniprotKB Accession | Q8NHM5 | |
|---|---|---|
| Alternative Name(s) | CXXC-type zinc finger protein 2, F-box and leucine-rich repeat protein 10, F-box protein FBL10, F-box/LRR-repeat protein 10, JmjC domain-containing histone demethylation protein 1B, Jumonji domain-containing EMSY-interactor methyltransferase motif protein (Protein JEMMA), Protein-containing CXXC domain 2, [Histone-H3]-lysine-36 demethylase 1B | |
| Eraser for PTM/s | H3K4me3, H3K36me2 | |
| EC number | 1.14.11.27 | |
| No. of coding genes | Lysine-specific demethylase 2B is coded by following 1 non-allelic gene/s | |
| Gene name | lysine (K)-specific demethylase 2B | |
| Gene symbol | KDM2B | |
| Promoter region (-700 TSS +300) | Get sequence | |
| Previous Symbol/s | FBXL10 | |
| Aliases | PCCX2, CXXC2, Fbl10, JHDM1B | |
| GeneID | 84678 | |
| HGNC | 13610 | |
| RefSeq mRNA | NM_001005366.1 | NM_032590.4 |
| RefSeq Protein | NP_001005366.1 | NP_115979.3 |
| TCGA Gene Expression (Firebrowse) | KDM2B | |
| mir Targets | KDM2B | |
| Pubmed | For more Information | |
Lysine demethylases Histone lysine demethylase PHF8, Lysine-specific demethylase 2A, Lysine-specific demethylase 2B, Lysine-specific demethylase 3A, Lysine-specific demethylase 3B, Lysine-specific demethylase 4A, Lysine-specific demethylase 4B, Lysine-specific demethylase 4C, Lysine-specific demethylase 4D, Lysine-specific demethylase 5A, Lysine-specific demethylase 5B, Lysine-specific demethylase 5C, Lysine-specific demethylase 5D, Lysine-specific demethylase 6A, Lysine-specific demethylase 6B, Lysine-specific demethylase 7, Lysine-specific demethylase 8, Lysine-specific demethylase NO66, Lysine-specific histone demethylase 1A, Lysine-specific histone demethylase 1B