Lysine-specific demethylase 8

KDM8 belongs to the JmJC domain containing protein family but exclusively lacks the PHD/Tudor domain for binding to DNA/Chromatin. It demethylates H3K36me2.

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Lysine-specific demethylase 8 infosheet
UniprotKB AccessionQ8N371
Alternative Name(s)JmjC domain-containing protein 5, Jumonji domain-containing protein 5
Eraser for PTM/s H3K36me2
EC number 1.14.11.27
No. of coding genesLysine-specific demethylase 8 is coded by following 1 non-allelic gene/s
Gene namejumonji domain containing 5
Gene symbolJMJD5
Promoter region (-700 TSS +300)Get sequence
Previous Symbol/s-
AliasesFLJ13798
GeneID79831
HGNC25840
RefSeq mRNANM_001145348.1NM_024773.2
RefSeq ProteinNP_001138820.1NP_079049.2
TCGA Gene Expression (Firebrowse)JMJD5
mir TargetsJMJD5
PubmedFor more Information

Lysine demethylases Histone lysine demethylase PHF8, Lysine-specific demethylase 2A, Lysine-specific demethylase 2B, Lysine-specific demethylase 3A, Lysine-specific demethylase 3B, Lysine-specific demethylase 4A, Lysine-specific demethylase 4B, Lysine-specific demethylase 4C, Lysine-specific demethylase 4D, Lysine-specific demethylase 5A, Lysine-specific demethylase 5B, Lysine-specific demethylase 5C, Lysine-specific demethylase 5D, Lysine-specific demethylase 6A, Lysine-specific demethylase 6B, Lysine-specific demethylase 7, Lysine-specific demethylase 8, Lysine-specific demethylase NO66, Lysine-specific histone demethylase 1A, Lysine-specific histone demethylase 1B