Lys-63-specific deubiquitinase BRCC36

BRCC36 is reported to catalyse the deubiquitination of gamma-H2A.X during DNA damage response.

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Lys-63-specific deubiquitinase BRCC36 infosheet
UniprotKB AccessionP46736
Alternative Name(s)BRCA1-A complex subunit BRCC36, BRCA1/BRCA2-containing complex subunit 3, BRCA1/BRCA2-containing complex subunit 36, BRISC complex subunit BRCC36
Eraser for PTM/s
EC number 3.4.19.-
No. of coding genesLys-63-specific deubiquitinase BRCC36 is coded by following 1 non-allelic gene/s
Gene nameBRCA1/BRCA2-containing complex, subunit 3
Gene symbolBRCC3
Promoter region (-700 TSS +300)Get sequence
Previous Symbol/sCXorf53
AliasesC6.1A, BRCC36
GeneID79184
HGNC24185
RefSeq mRNANM_001018055.1NM_024332.2
RefSeq ProteinNP_001018065.1NP_077308.1
TCGA Gene Expression (Firebrowse)BRCC3
mir TargetsBRCC3
PubmedFor more Information

Lysine deubiquitinases Histone H2A deubiquitinase MYSM1, Lys-63-specific deubiquitinase BRCC36, Ubiquitin carboxyl-terminal hydrolase 16, Ubiquitin carboxyl-terminal hydrolase 22, Ubiquitin carboxyl-terminal hydrolase 3