Histone-lysine N-methyltransferase SETD2

SETD2 is known for methylation of lysine 36 of histone H3.

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Histone-lysine N-methyltransferase SETD2 infosheet
UniprotKB AccessionQ9BYW2
Alternative Name(s)HIF-1, Huntingtin yeast partner B, Huntingtin-interacting protein 1 (HIP-1), Huntingtin-interacting protein B, Lysine N-methyltransferase 3A, SET domain-containing protein 2 (hSET2), p231HBP
Writer for PTM/s H3K36me3
EC number 2.1.1.43
No. of coding genesHistone-lysine N-methyltransferase SETD2 is coded by following 1 non-allelic gene/s
Gene nameSET domain containing 2
Gene symbolSETD2
Promoter region (-700 TSS +300)Get sequence
Previous Symbol/s-
AliasesHYPB, HIF-1, KIAA1732, FLJ23184, KMT3A
GeneID29072
HGNC18420
RefSeq mRNANM_014159.6
RefSeq ProteinNP_054878.5
TCGA Gene Expression (Firebrowse)SETD2
mir TargetsSETD2
PubmedFor more Information

Lysine methyltransferases Histone-lysine N-methyltransferase EZH1, Histone-lysine N-methyltransferase EZH2, Histone-lysine N-methyltransferase MLL, Histone-lysine N-methyltransferase MLL2, Histone-lysine N-methyltransferase MLL3, Histone-lysine N-methyltransferase MLL4, Histone-lysine N-methyltransferase MLL5, Histone-lysine N-methyltransferase NSD3, Histone-lysine N-methyltransferase PRDM9, Histone-lysine N-methyltransferase SETD1A, Histone-lysine N-methyltransferase SETD1B, Histone-lysine N-methyltransferase SETD2, Histone-lysine N-methyltransferase SETD7, Histone-lysine N-methyltransferase SETD8, Histone-lysine N-methyltransferase SETDB1, Histone-lysine N-methyltransferase SETDB2, Histone-lysine N-methyltransferase SETMAR, Histone-lysine N-methyltransferase SUV39H1, Histone-lysine N-methyltransferase SUV39H2, Histone-lysine N-methyltransferase SUV420H1, Histone-lysine N-methyltransferase SUV420H2, Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific, Histone-lysine N-methyltransferase, H3 lysine-79 specific, Histone-lysine N-methyltransferase, H3 lysine-9 specific 3, Histone-lysine N-methyltransferase, H3 lysine-9 specific 5, N-lysine methyltransferase SMYD2, PR domain zinc finger protein 2, Probable histone-lysine N-methyltransferase ASH1L, Probable histone-lysine N-methyltransferase NSD2, SET and MYND domain-containing protein 3