Histone-lysine N-methyltransferase SETD1A

SETD1A specifically methylates H3K4 at the transcriptional start site.

Download table as Excel
Histone-lysine N-methyltransferase SETD1A infosheet
UniprotKB AccessionO15047
Alternative Name(s)Lysine N-methyltransferase 2F, SET domain-containing protein 1A (hSET1A), Set1/Ash2 histone methyltransferase complex subunit SET1
Writer for PTM/s H3K4me3
EC number 2.1.1.43
No. of coding genesHistone-lysine N-methyltransferase SETD1A is coded by following 1 non-allelic gene/s
Gene nameSET domain containing 1A
Gene symbolSETD1A
Promoter region (-700 TSS +300)Get sequence
Previous Symbol/s-
AliasesKIAA0339, Set1, KMT2F
GeneID9739
HGNC29010
RefSeq mRNANM_014712.1
RefSeq ProteinNP_055527.1
TCGA Gene Expression (Firebrowse)SETD1A
mir TargetsSETD1A
PubmedFor more Information

Lysine methyltransferases Histone-lysine N-methyltransferase EZH1, Histone-lysine N-methyltransferase EZH2, Histone-lysine N-methyltransferase MLL, Histone-lysine N-methyltransferase MLL2, Histone-lysine N-methyltransferase MLL3, Histone-lysine N-methyltransferase MLL4, Histone-lysine N-methyltransferase MLL5, Histone-lysine N-methyltransferase NSD3, Histone-lysine N-methyltransferase PRDM9, Histone-lysine N-methyltransferase SETD1A, Histone-lysine N-methyltransferase SETD1B, Histone-lysine N-methyltransferase SETD2, Histone-lysine N-methyltransferase SETD7, Histone-lysine N-methyltransferase SETD8, Histone-lysine N-methyltransferase SETDB1, Histone-lysine N-methyltransferase SETDB2, Histone-lysine N-methyltransferase SETMAR, Histone-lysine N-methyltransferase SUV39H1, Histone-lysine N-methyltransferase SUV39H2, Histone-lysine N-methyltransferase SUV420H1, Histone-lysine N-methyltransferase SUV420H2, Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific, Histone-lysine N-methyltransferase, H3 lysine-79 specific, Histone-lysine N-methyltransferase, H3 lysine-9 specific 3, Histone-lysine N-methyltransferase, H3 lysine-9 specific 5, N-lysine methyltransferase SMYD2, PR domain zinc finger protein 2, Probable histone-lysine N-methyltransferase ASH1L, Probable histone-lysine N-methyltransferase NSD2, SET and MYND domain-containing protein 3