Histone-lysine N-methyltransferase EZH1

EZH1 is part of PRC (Polycomb repressor complex) and known for mediating H3K27 mono and di methylation.

Download table as Excel
Histone-lysine N-methyltransferase EZH1 infosheet
UniprotKB AccessionQ92800
Alternative Name(s)Enhancer of zeste homolog 1
Writer for PTM/s H3K27me1, H3K27me2
EC number 2.1.1.43
No. of coding genesHistone-lysine N-methyltransferase EZH1 is coded by following 1 non-allelic gene/s
Gene nameenhancer of zeste homolog 1 (Drosophila)
Gene symbolEZH1
Promoter region (-700 TSS +300)Get sequence
Previous Symbol/s-
AliasesKIAA0388, KMT6B
GeneID2145
HGNC3526
RefSeq mRNANM_001991.3
RefSeq ProteinNP_001982.2
TCGA Gene Expression (Firebrowse)EZH1
mir TargetsEZH1
PubmedFor more Information

Lysine methyltransferases Histone-lysine N-methyltransferase EZH1, Histone-lysine N-methyltransferase EZH2, Histone-lysine N-methyltransferase MLL, Histone-lysine N-methyltransferase MLL2, Histone-lysine N-methyltransferase MLL3, Histone-lysine N-methyltransferase MLL4, Histone-lysine N-methyltransferase MLL5, Histone-lysine N-methyltransferase NSD3, Histone-lysine N-methyltransferase PRDM9, Histone-lysine N-methyltransferase SETD1A, Histone-lysine N-methyltransferase SETD1B, Histone-lysine N-methyltransferase SETD2, Histone-lysine N-methyltransferase SETD7, Histone-lysine N-methyltransferase SETD8, Histone-lysine N-methyltransferase SETDB1, Histone-lysine N-methyltransferase SETDB2, Histone-lysine N-methyltransferase SETMAR, Histone-lysine N-methyltransferase SUV39H1, Histone-lysine N-methyltransferase SUV39H2, Histone-lysine N-methyltransferase SUV420H1, Histone-lysine N-methyltransferase SUV420H2, Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific, Histone-lysine N-methyltransferase, H3 lysine-79 specific, Histone-lysine N-methyltransferase, H3 lysine-9 specific 3, Histone-lysine N-methyltransferase, H3 lysine-9 specific 5, N-lysine methyltransferase SMYD2, PR domain zinc finger protein 2, Probable histone-lysine N-methyltransferase ASH1L, Probable histone-lysine N-methyltransferase NSD2, SET and MYND domain-containing protein 3