E3 ubiquitin-protein ligase UBR2

UBR2 is shown to ubiquitinate histone H2A which leads into transcriptional silencing.

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E3 ubiquitin-protein ligase UBR2 infosheet
UniprotKB AccessionQ8IWV8
Alternative Name(s)N-recognin-2, Ubiquitin-protein ligase E3-alpha-2, Ubiquitin-protein ligase E3-alpha-II
Writer for PTM/s
EC number 6.3.2.-
No. of coding genesE3 ubiquitin-protein ligase UBR2 is coded by following 1 non-allelic gene/s
Gene nameubiquitin protein ligase E3 component n-recognin 2
Gene symbolUBR2
Promoter region (-700 TSS +300)Get sequence
Previous Symbol/sC6orf133
AliasesbA49A4.1, dJ392M17.3, KIAA0349
GeneID23304
HGNC21289
RefSeq mRNANM_015255.2
RefSeq ProteinNP_056070.1
TCGA Gene Expression (Firebrowse)UBR2
mir TargetsUBR2
PubmedFor more Information

Lysine ubiquitinases E3 ubiquitin-protein ligase BRE1A, E3 ubiquitin-protein ligase BRE1B, E3 ubiquitin-protein ligase DTX3L, E3 ubiquitin-protein ligase HUWE1, E3 ubiquitin-protein ligase RBX1, E3 ubiquitin-protein ligase RING1, E3 ubiquitin-protein ligase RING2, E3 ubiquitin-protein ligase RNF168, E3 ubiquitin-protein ligase RNF8, E3 ubiquitin-protein ligase UBR2, E3 ubiquitin-protein ligase UHRF1, V(D)J recombination-activating protein 1