E3 ubiquitin-protein ligase RING2

RING1B is part of polycomb repressive complex 1 (PRC1) which mediates ubiquitination of H2A lysine 119.

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E3 ubiquitin-protein ligase RING2 infosheet
UniprotKB AccessionQ99496
Alternative Name(s)Huntingtin-interacting protein 2-interacting protein 3 (HIP2-interacting protein 3), Protein DinG, RING finger protein 1B (RING1b), RING finger protein 2, RING finger protein BAP-1
Writer for PTM/s H2AK119ub, H2AK121ub
EC number 6.3.2.-
No. of coding genesE3 ubiquitin-protein ligase RING2 is coded by following 1 non-allelic gene/s
Gene namering finger protein 2
Gene symbolRNF2
Promoter region (-700 TSS +300)Get sequence
Previous Symbol/s-
AliasesBAP-1, BAP1, DING, HIPI3, RING1B, RING2
GeneID6045
HGNC10061
RefSeq mRNANM_007212.3
RefSeq ProteinNP_009143.1
TCGA Gene Expression (Firebrowse)RNF2
mir TargetsRNF2
PubmedFor more Information

Lysine ubiquitinases E3 ubiquitin-protein ligase BRE1A, E3 ubiquitin-protein ligase BRE1B, E3 ubiquitin-protein ligase DTX3L, E3 ubiquitin-protein ligase HUWE1, E3 ubiquitin-protein ligase RBX1, E3 ubiquitin-protein ligase RING1, E3 ubiquitin-protein ligase RING2, E3 ubiquitin-protein ligase RNF168, E3 ubiquitin-protein ligase RNF8, E3 ubiquitin-protein ligase UBR2, E3 ubiquitin-protein ligase UHRF1, V(D)J recombination-activating protein 1