E3 ubiquitin-protein ligase HUWE1

This E3 ubiquitin protein is reported for ubiquitination activity for all histone types.

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E3 ubiquitin-protein ligase HUWE1 infosheet
UniprotKB AccessionQ7Z6Z7
Alternative Name(s)ARF-binding protein 1 (ARF-BP1), HECT, UBA and WWE domain-containing protein 1, Homologous to E6AP carboxyl terminus homologous protein 9 (HectH9), Large structure of UREB1 (LASU1), Mcl-1 ubiquitin ligase E3 (Mule), Upstream regulatory element-binding protein 1 (URE-B1, URE-binding protein 1)
Writer for PTM/s
EC number 6.3.2.-
No. of coding genesE3 ubiquitin-protein ligase HUWE1 is coded by following 1 non-allelic gene/s
Gene nameHECT, UBA and WWE domain containing 1
Gene symbolHUWE1
Promoter region (-700 TSS +300)Get sequence
Previous Symbol/s-
AliasesIb772, KIAA0312, UREB1
GeneID10075
HGNC30892
RefSeq mRNANM_031407.4
RefSeq ProteinNP_113584.3
TCGA Gene Expression (Firebrowse)HUWE1
mir TargetsHUWE1
PubmedFor more Information

Lysine ubiquitinases E3 ubiquitin-protein ligase BRE1A, E3 ubiquitin-protein ligase BRE1B, E3 ubiquitin-protein ligase DTX3L, E3 ubiquitin-protein ligase HUWE1, E3 ubiquitin-protein ligase RBX1, E3 ubiquitin-protein ligase RING1, E3 ubiquitin-protein ligase RING2, E3 ubiquitin-protein ligase RNF168, E3 ubiquitin-protein ligase RNF8, E3 ubiquitin-protein ligase UBR2, E3 ubiquitin-protein ligase UHRF1, V(D)J recombination-activating protein 1