Back to Epidrugs Infobase

Drug Name:
Category: PADi
Description: Pan PADi: YW3-56, activates p53 target genes to inhibit cancer growth by
controlling cell cycle and by inducing breast cancer cell death. It also
activates genes SESN2 and DDIT4 which regulate the mTOR pathway.
Synonyms:

Structural Information:
2D Image:
Structure 2D: Download
Molecular Formula: C27H32ClN5O2
Molecular Weight: 494.036 g/mol
IUPAC name: N-[(2S)-5-[(1-amino-2-chloroethylidene)amino]-1-(benzylamino)-1-oxopentan-2-yl]-6-(dimethylamino)nap
hthalene-2-carboxamide
InChI: InChI=1S/C27H32ClN5O2/c1-33(2)23-13-12-20-15-22(11-10-21(20)16-23)26(34)32-24(9-
6-14-30-25(29)17-28)27(35)31-18-19-7-4-3-5-8-19/h3-5,7-8,10-13,15-16,24H,6,9,14,
17-18H2,1-2H3,(H2,29,30)(H,31,35)(H,32,34)/t24-/m0/s1
SMILES: CN(C)C1=CC2=C(C=C1)C=C(C=C2)C(=O)NC(CCCN=C(CCl)N)C(=O)NCC3=C
C=CC=C3

Clinical Information:
FDA status: Experimental
FDA_UNII: -
Clinical Trials : Not recruiting
Clinical Trials


Bioassay Information: YW3-56
Source: PubChem Bioassay database
No information available for YW3-56


References:
Literature Reference: PMC3406678, PMC4394025
Literature: Pubmed
Google Scholar
PubChem ID: 56970298
PubChem Citation: National Center for Biotechnology Information. PubChem Compound Database; CID=56970298, https://pubchem.ncbi.nlm.nih.gov/compound/56970298 (accessed Mar. 8, 2019).
ChEMBL ID: CHEMBL3682418
ZINC DB: -
LiverTox: Not available for YW3-56
Human Metabolome database : HMDB