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Drug Name:
Category: PADi
Description: Cl-amidine- PADI , strongly affects the expression of several cell cycle genes
implicated in tumor progression, including p21, GADD45?, and Ki67.
Synonyms:

Structural Information:
2D Image:
Structure 2D: Download
Molecular Formula: C14H19ClN4O2
Molecular Weight: 310.782 g/mol
IUPAC name: N-[(2S)-1-amino-5-[(1-amino-2-chloroethylidene)amino]-1-oxopentan-2-yl]benzamide
InChI: InChI=1S/C14H19ClN4O2/c15-9-12(16)18-8-4-7-11(13(17)20)19-14(21)10-5-2-1-3-6-10/
h1-3,5-6,11H,4,7-9H2,(H2,16,18)(H2,17,20)(H,19,21)/t11-/m0/s1
SMILES: NC(=O)[C@H](CCCNC(=N)CCl)NC(=O)c1ccccc1

Clinical Information:
FDA status: Experimental
FDA_UNII: -
Clinical Trials : Not recruiting
Clinical Trials

Source: PubChem Bioassay
Bioassay Information
AID CID SID Assay Name Target GI Target GeneID Bioactivity Outcome
712874 24970878 163326132 Selectivity ratio of Kinact to
Ki for PAD1 to Kinact to Ki
for PAD4
Unspecified
712875 24970878 163326132 Selectivity ratio of Kinact to
Ki for PAD1 to Kinact to Ki
for PAD3
Unspecified
712876 24970878 163326132 Ratio of Kinact to Ki for PAD4 Unspecified
712877 24970878 163326132 Selectivity ratio of Kinact to
Ki for PAD1 to Kinact to Ki
for PAD2
Unspecified
712878 24970878 163326132 Ratio of Kinact to Ki for PAD3 Unspecified

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References:
Literature Reference: PMC3572853
Literature: Pubmed
Google Scholar
PubChem ID: 24970878
PubChem Citation: National Center for Biotechnology Information. PubChem Compound Database; CID=24970878, https://pubchem.ncbi.nlm.nih.gov/compound/24970878 (accessed Mar. 8, 2019).
ChEMBL ID: CHEMBL1962361
ZINC DB: -
LiverTox: Not available for Cl-amidine
Human Metabolome database : HMDB