Version II
 Gene List
 Keyword Search
 Interaction Network


Head and neck cancer is the sixth common malignancy and a major cause of cancer morbidity and mortality worldwide and oral cavity is one of the most commonly affected sites. Worldwide over 350,000 to 400,000 new cases of cancer are reported each year. Cancers of Head and Neck comprises ~24.1 % of total cancers seen at the Tata Memorial Centre, Mumbai, of these ~13.5 % are from the Oral cavity. In the post genomic era, efforts to understand oral cancer are aimed at obtaining genomic and proteomic profiles which generate enormous data. Thus the challenge is to analyze the data effectively and utilize the information for diagnosis, prognosis and treatment.

OrCGDB ( oral cancer gene database has information for only 15 genes without a search engine and interaction network. Our first database with 242 genes was made in 2007 and is available at ( The present database, version II, has been updated to include 374 genes. It has been developed as a user friendly site that would provide the scientist, information and external links from one place.


Click here to get list of all 374 genes in the database. For each gene, hyperlink to its PubMed reference is provided. Clicking on gene name gives detailed information on aliases, function, chromosomal location, mutations and SNPs, mRNA expression, Protein information, pathways involved and interacting proteins, expression of genes in different tissues, and clinical correlates.


Keyword search using Gene name or gene symbol, Chromosomal location, CGH (in %), and Molecular weight. Advanced search option for multiple searches from the above parameters is also available.


Interaction Network shows the interaction between genes for particular biological processes and molecular functions. The connecting line between the two genes gives the PubMed reference for their interactions. Clicking on the gene name gives detailed information. 

Oral Cancer Gene Database (Version II) consists of 374 genes which has been published in :

Nikhil Sureshkumar Gadewal , Surekha Mahesh Zingde., Database and interaction network  of genes involved in oral cancer, Bioinformation, 6 (4) 169-170, 2011. (Full-text Pdf)


For suggestion and comments:  Curator: Mr. Nikhil S. Gadewal (

                                                   Science Editor: Dr. Surekha M. Zingde  (


**This database is best viewed in Internet Explorer**